Primaxin and Decadron drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Primaxin (cilastatin sodium; imipenem) and Decadron (dexamethasone). Common drug interactions include multi-organ failure among females and death among males.

The phase IV clinical study analyzes what interactions people have when they take Primaxin and Decadron. It is created by eHealthMe based on reports of 29 people who take the same drugs from the FDA, and is updated regularly.

What is Primaxin?

Primaxin has active ingredients of cilastatin sodium; imipenem. eHealthMe is studying from 4,540 Primaxin users. Check the latest studies of Primaxin.

What is Decadron?

Decadron has active ingredients of dexamethasone. It is often used in multiple myeloma. eHealthMe is studying from 47,210 Decadron users. Check the latest studies of Decadron.

On Jul, 18, 2026

29 people who take Primaxin and Decadron together, and have interactions are studied.

Primaxin and Decadron drug interactions.

What are the common drug interactions of Primaxin and Decadron, by gender? *:

female:

Multi-organ failure (multisystem organ failure)
Organ failure
Platelet count decreased
Pleural effusion (water on the lungs)
Pneumonia bacterial (pneumonia associated with bacterial infection)
Vein disorder
White blood cell count decreased
White blood cell count increased
Neutropenia (an abnormally low number of neutrophils)
Caecitis (inflammation of the cecum)

male:

Death
Asthenia (weakness)
Dyspnoea (difficult or laboured respiration)
Herpes zoster
Oral herpes (viral infection of mouth)
Pyrexia (fever)
Weight decreased
Blood bilirubin increased
Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body)
Hepatic function abnormal

What are the common drug interactions of Primaxin and Decadron, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Caecitis (inflammation of the cecum)
Colitis ischaemic (due to infection of intestine impaired blood supply to colon)
Hypersensitivity
Sepsis (a severe blood infection that can lead to organ failure and death)
Atelectasis (partial or complete collapse of the lung)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Pancreatitis (inflammation of pancreas)
Platelet count increased
Activated partial thromboplastin time prolonged
Angiopathy (generic term for a disease of the blood vessels)

40-49:

Body temperature increased
Constipation
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Ileus (a painful obstruction of the ileum or other part of the intestine)
Neutropenia (an abnormally low number of neutrophils)

50-59:

Cytomegalovirus infection
Epstein-barr virus infection
Aortitis (inflammation of the aortic wall)

60+:

Death
Abdominal distension
Febrile neutropenia (fever with reduced white blood cells)
Haematuria present (presence of blood in urine due to trauma)
Lethargy (tiredness)
Neutropenia (an abnormally low number of neutrophils)
Oedema lower limb (fluid collection in tissue of lower leg)
Thrombocytopenia (decrease of platelets in blood)
Tremor (trembling or shaking movements in one or more parts of your body)
Diarrhoea

What are the existing conditions these people have? *

Breast Cancer: 4 people, 13.79%
Nausea (feeling of having an urge to vomit): 3 people, 10.34%
Sepsis (a severe blood infection that can lead to organ failure and death): 2 people, 6.90%

* Approximation only. Some reports may have incomplete information.

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