Primidone and Breo ellipta drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Primidone (primidone) and Breo ellipta (fluticasone furoate; vilanterol trifenatate). Common drug interactions include fungal infection among females and myocardial infarction among males.
The phase IV clinical study analyzes what interactions people have when they take Primidone and Breo ellipta. It is created by eHealthMe based on reports of 78 people who take the same drugs from the FDA, and is updated regularly.
What is Primidone?
Primidone has active ingredients of primidone. It is often used in essential tremor. eHealthMe is studying from 10,474 Primidone users. Check the latest studies of Primidone.
What is Breo ellipta?
Breo ellipta has active ingredients of fluticasone furoate; vilanterol trifenatate. It is often used in asthma. eHealthMe is studying from 37,362 Breo ellipta users. Check the latest studies of Breo ellipta.
78 people who take Primidone and Breo ellipta together, and have interactions are studied.

What are the common drug interactions of Primidone and Breo Ellipta, by gender? *:
female:
- Fungal infection
- Gingival bleeding (bleeding gums)
- Glaucoma (increased fluid pressure in the eye with vision loss)
- Hemiparesis (weakness on one side of the body)
- Injection site discomfort
- Injection site pain
- Injury
- Intervertebral disc degeneration (spinal disc degeneration)
- Mobility decreased (ability to move is reduced)
- Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
male:
- Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
- Suicidal ideation
- Anger
- Bladder cancer
- Blood pressure increased
- Decreased appetite
- Drug ineffective
- Foot fracture
- Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)
- Insomnia (sleeplessness)
What are the common drug interactions of Primidone and Breo Ellipta, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Drug ineffective
- Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)
- Ligament rupture (tear in ligament)
- Malaise (a feeling of general discomfort or uneasiness)
- Tendon rupture (tear of tendon)
- Visual impairment
- Chronic kidney disease
- Somnolence (a state of near-sleep, a strong desire for sleep)
- Suicidal ideation
- Allergy to plants
50-59:
- Chronic kidney disease
- Renal injury (kidney injury)
- Anxiety
- Gingival bleeding (bleeding gums)
- Meningitis aseptic (a condition that causes the membranes covering your brain and spinal cord to become inflamed)
- Nervousness
- Oxygen saturation decreased
- Pneumonia
- Pyrexia (fever)
- Sensitivity of teeth
60+:
- Pneumonia
- Oedema (fluid collection in tissue)
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Drug ineffective
- Blood pressure decreased
- Fatigue (feeling of tiredness)
- Interstitial lung disease
- Thrombosis (formation of a blood clot inside a blood vessel)
- Upper limb fracture
- Ageusia (loss of taste functions of the tongue)
What are the existing conditions these people have? *
- Immunodeficiency Common Variable: 16 people, 20.51%
- Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 11 people, 14.10%
- Pain: 9 people, 11.54%
- Tremor (trembling or shaking movements in one or more parts of your body): 8 people, 10.26%
- High Blood Cholesterol: 8 people, 10.26%
- High Blood Pressure: 8 people, 10.26%
- Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 6 people, 7.69%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 7.69%
- Cataplexy (loss of muscle tone accompanied by full conscious awareness): 6 people, 7.69%
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 6 people, 7.69%
* Approximation only. Some reports may have incomplete information.
Do you take Primidone and Breo ellipta?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Primidone (10,474 reports)
- Breo ellipta (37,362 reports)
Browse all drug interactions of Primidone and Breo ellipta:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Primidone:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Breo ellipta:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Primidone and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Breo ellipta and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on primidone and fluticasone furoate; vilanterol trifenatate (the active ingredients of Primidone and Breo ellipta, respectively), and Primidone and Breo ellipta (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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