Primidone and Dyazide drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Primidone (primidone) and Dyazide (hydrochlorothiazide; triamterene). Common drug interactions include abscess limb among females and abdominal pain among males.
The phase IV clinical study analyzes what interactions people have when they take Primidone and Dyazide. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.
What is Primidone?
Primidone has active ingredients of primidone. It is often used in essential tremor. eHealthMe is studying from 10,474 Primidone users. Check the latest studies of Primidone.
What is Dyazide?
Dyazide has active ingredients of hydrochlorothiazide; triamterene. It is often used in high blood pressure. eHealthMe is studying from 11,506 Dyazide users. Check the latest studies of Dyazide.
26 people who take Primidone and Dyazide together, and have interactions are studied.

What are the common drug interactions of Primidone and Dyazide, by gender? *:
female:
- Abscess limb (limb infection)
- Cellulitis (infection under the skin)
- Diarrhoea
- Impaired healing
- Injection site erythema (redness at injection site)
- Injection site pain
- Injection site swelling
- Injection site ulcer
- Pain in extremity
- Localised infection (infection at the single location)
male:
- Abdominal pain
- Asthenia (weakness)
- Fatigue (feeling of tiredness)
- Heart rate increased
- Intervertebral disc protrusion (spinal disc protrusion)
- Intestinal obstruction
- Lymphoma (cancer that begins in immune system cells)
- Mucosal erosion (peeling off of mucous membrane)
- Nausea (feeling of having an urge to vomit)
- Oral pain
What are the common drug interactions of Primidone and Dyazide, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Drug hypersensitivity
- Feeling hot
- Pruritus (severe itching of the skin)
- Sensory disturbance (sense disturbance)
- Throat tightness
- Urticaria (rash of round, red welts on the skin that itch intensely)
40-49:
- Electrocardiogram qt prolonged
- Fatigue (feeling of tiredness)
- Middle insomnia (difficulty returning to sleep after awakening either in the middle of the night)
50-59:
- Abdominal pain
- Back disorder
- Connective tissue disorder (any disease that has the connective tissues of the body)
- Constipation
- Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
- Intervertebral disc protrusion (spinal disc protrusion)
60+:
- Diarrhoea
- Abscess limb (limb infection)
- Oedema peripheral (superficial swelling)
- Procedural pain
- Injection site warmth
- Osteoarthritis (a joint disease caused by cartilage loss in a joint)
- Staphylococcus test positive
- Arthralgia (joint pain)
- Asthenia (weakness)
- Bacterial infection
What are the existing conditions these people have? *
- Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 6 people, 23.08%
- Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 5 people, 19.23%
- Constipation: 5 people, 19.23%
- Itching: 4 people, 15.38%
- Arthritis (form of joint disorder that involves inflammation of one or more joints): 3 people, 11.54%
- Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 7.69%
- Joint Pain: 2 people, 7.69%
* Approximation only. Some reports may have incomplete information.
Do you take Primidone and Dyazide?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Primidone and Dyazide:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Primidone:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Dyazide:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Primidone and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Dyazide and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on primidone and hydrochlorothiazide; triamterene (the active ingredients of Primidone and Dyazide, respectively), and Primidone and Dyazide (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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