Primidone and Nabumetone drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Primidone (primidone) and Nabumetone (nabumetone). Common drug interactions include weight decreased among females and akinesia among males.
The phase IV clinical study analyzes what interactions people have when they take Primidone and Nabumetone. It is created by eHealthMe based on reports of 37 people who take the same drugs from the FDA, and is updated regularly.
What is Primidone?
Primidone has active ingredients of primidone. It is often used in essential tremor. eHealthMe is studying from 10,474 Primidone users. Check the latest studies of Primidone.
What is Nabumetone?
Nabumetone has active ingredients of nabumetone. It is often used in arthritis. eHealthMe is studying from 9,554 Nabumetone users. Check the latest studies of Nabumetone.
37 people who take Primidone and Nabumetone together, and have interactions are studied.

What are the common drug interactions of Primidone and Nabumetone, by gender? *:
female:
- Weight decreased
- Insomnia (sleeplessness)
- Balance disorder
- Hypoaesthesia (reduced sense of touch or sensation)
- Arrhythmia (irregular heartbeat)
- Arthropathy
- Cardiac disorder
- Cataract (clouding of the lens inside the eye)
- Hypotension (abnormally low blood pressure)
- Infection
male:
- Akinesia (loss of control of voluntary muscle movements)
- Back pain
- Feeling cold
- Hallucination (an experience involving the perception of something not present)
- International normalised ratio increased
- Loss of consciousness
- Memory impairment
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Thrombocytopenia (decrease of platelets in blood)
What are the common drug interactions of Primidone and Nabumetone, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Back pain
- Diarrhoea
- Drug ineffective
- International normalised ratio increased
- Urticaria (rash of round, red welts on the skin that itch intensely)
- Weight decreased
50-59:
- Balance disorder
- Hypoaesthesia (reduced sense of touch or sensation)
- Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
- Ataxia (loss of full control of bodily movements)
- Cerebellar atrophy (degeneration of the section of the brain responsible for balance, voluntary muscle movements)
- Cerebral atrophy (decrement in size of brain)
- Cerebral infarction (less blood supply to brain resulting tissue damage)
- Cerebral small vessel ischaemic disease (inadequate blood supply to small blood vessel of brain)
- Chronic kidney disease
- Confusional state
60+:
- Sinusitis (inflammation of sinus)
- Anaemia (lack of blood)
- Hypotension (abnormally low blood pressure)
- Infection
- Intestinal obstruction
- Iritis (painful inflammation of the iris of the eye)
- Ocular hypertension (intraocular pressure higher than normal)
- Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
- Pulmonary thrombosis (scarring in the lungs)
- Small intestinal obstruction (blockage in small intestine)
What are the existing conditions these people have? *
- Asthma: 11 people, 29.73%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 18.92%
- Immunodeficiency Common Variable: 7 people, 18.92%
- Seizures (abnormal excessive or synchronous neuronal activity in the brain): 7 people, 18.92%
- Pain: 7 people, 18.92%
- Depression: 6 people, 16.22%
- Headache (pain in head): 5 people, 13.51%
- Nausea (feeling of having an urge to vomit): 5 people, 13.51%
- Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 5 people, 13.51%
- Eye Disorder: 4 people, 10.81%
* Approximation only. Some reports may have incomplete information.
Do you take Primidone and Nabumetone?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Primidone (10,474 reports)
- Nabumetone (9,554 reports)
Browse all drug interactions of Primidone and Nabumetone:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Primidone:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Nabumetone:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Primidone and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Nabumetone and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Hung SC, Liao KF, Hung HC, Lin CL, Lai SW, Lin CH, "Nabumetone use and risk of acute pancreatitis in a case-control study", Pancreatology, 2016 Jun .
- Hung SC, Liao KF, Hung HC, Lin CL, Lai SW, Lin CH, "Nabumetone use and risk of acute pancreatitis in a case-control study", Pancreatology, 2016 Jun .
How the study uses the data?
The study uses data from the FDA. It is based on primidone and nabumetone (the active ingredients of Primidone and Nabumetone, respectively), and Primidone and Nabumetone (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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