Primidone and Serevent drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Primidone (primidone) and Serevent (salmeterol xinafoate). Common drug interactions include antinuclear factor positive among females and blood pressure decreased among males.

The phase IV clinical study analyzes what interactions people have when they take Primidone and Serevent. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Primidone?

Primidone has active ingredients of primidone. It is often used in essential tremor. eHealthMe is studying from 10,474 Primidone users. Check the latest studies of Primidone.

What is Serevent?

Serevent has active ingredients of salmeterol xinafoate. It is often used in asthma. eHealthMe is studying from 15,586 Serevent users. Check the latest studies of Serevent.



On Jul, 24, 2026

13 people who take Primidone and Serevent together, and have interactions are studied.

Primidone and Serevent drug interactions.

What are the common drug interactions of Primidone and Serevent, by gender? *:

female:

  1. Antinuclear factor positive
  2. Anxiety
  3. Atrophy (wasting away of a part of the body)
  4. Balance disorder
  5. Blood pressure increased
  6. Body height decreased
  7. Bronchitis chronic (inflammation of the mucous membrane in the bronchial tubes- chronic)
  8. Chest discomfort
  9. Chest pain
  10. Cholecystitis (infection of gallbladder)

male:

  1. Blood pressure decreased
  2. Chest pain
  3. Disorientation (disability in which the senses of time, direction, and recognition of people and places)
  4. Drug ineffective
  5. Dry mouth
  6. Dysphonia (speech disorder attributable to a disorder of phonation)
  7. Dyspnoea (difficult or laboured respiration)
  8. Pulmonary embolism (blockage of the main artery of the lung)

What are the common drug interactions of Primidone and Serevent, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Blood cholesterol increased
  2. Anxiety
  3. Atrophy (wasting away of a part of the body)
  4. Balance disorder
  5. Body height decreased
  6. Bronchitis chronic (inflammation of the mucous membrane in the bronchial tubes- chronic)
  7. Chest pain
  8. Cholecystitis (infection of gallbladder)
  9. Difficulty in walking
  10. Dry skin

60+:

  1. Dyspnoea (difficult or laboured respiration)
  2. Antinuclear factor positive
  3. Dysphonia (speech disorder attributable to a disorder of phonation)
  4. Haemorrhage (bleeding)
  5. Hyperhidrosis (abnormally increased sweating)
  6. Muscle spasms (muscle contraction)
  7. Palpitations (feelings or sensations that your heart is pounding or racing)
  8. Pulmonary embolism (blockage of the main artery of the lung)
  9. Rheumatoid factor positive
  10. Systemic lupus erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue)

What are the existing conditions these people have? *

  1. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 4 people, 30.77%
  2. Rhinorrhea (watery mucus discharge from the nose): 1 person, 7.69%
  3. High Blood Cholesterol: 1 person, 7.69%
  4. Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 1 person, 7.69%
  5. Bronchitis Chronic (inflammation of the mucous membrane in the bronchial tubes- chronic): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Primidone and Serevent?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Primidone and Serevent:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Primidone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Serevent:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Primidone and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Serevent and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on primidone and salmeterol xinafoate (the active ingredients of Primidone and Serevent, respectively), and Primidone and Serevent (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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