Primidone and Welchol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Primidone (primidone) and Welchol (colesevelam hydrochloride). Common drug interactions include ageusia among females and cystitis among males.

The phase IV clinical study analyzes what interactions people have when they take Primidone and Welchol. It is created by eHealthMe based on reports of 35 people who take the same drugs from the FDA, and is updated regularly.

What is Primidone?

Primidone has active ingredients of primidone. It is often used in essential tremor. eHealthMe is studying from 10,474 Primidone users. Check the latest studies of Primidone.

What is Welchol?

Welchol has active ingredients of colesevelam hydrochloride. It is often used in high blood cholesterol. eHealthMe is studying from 11,309 Welchol users. Check the latest studies of Welchol.

On Jul, 21, 2026

35 people who take Primidone and Welchol together, and have interactions are studied.

Primidone and Welchol drug interactions.

What are the common drug interactions of Primidone and Welchol, by gender? *:

female:

Ageusia (loss of taste functions of the tongue)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Decreased appetite
Dyspepsia (indigestion)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Malaise (a feeling of general discomfort or uneasiness)
Migraine (headache)
Gingival bleeding (bleeding gums)
Maculopathy (a condition or disease of the macula, the small spot in the retina where vision is keenest)
Abdominal discomfort

male:

Cystitis (inflammation of the wall of the bladder)
Eye swelling
Hospitalisation
Malaise (a feeling of general discomfort or uneasiness)
Malignant melanoma in situ (early stage of cancer in melanocyte)
Renal failure (kidney dysfunction)
Small intestinal obstruction (blockage in small intestine)
Headache (pain in head)
Hypertension (high blood pressure)
Pruritus (severe itching of the skin)

What are the common drug interactions of Primidone and Welchol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Gingival bleeding (bleeding gums)
Maculopathy (a condition or disease of the macula, the small spot in the retina where vision is keenest)

40-49:

Azotaemia (excess of urea or other nitrogenous compounds in the blood)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Concussion (short loss of normal brain function in response to a head injury)
Contusion (a type of hematoma of tissue in which capillaries)
Dementia (madness)
Diabetic gastroparesis (paralysis of the muscles of the stomach caused by diabetes)
Dysphagia (a condition in which swallowing is difficult or painful)
Ear pain
Gastritis (inflammation of stomach)
Gastroenteritis (inflammation of stomach and intestine)

50-59:

Cystitis (inflammation of the wall of the bladder)
Eye swelling
Headache (pain in head)
Hypertension (high blood pressure)
Pruritus (severe itching of the skin)
Road traffic accident
Skin discolouration (change of skin colour)
Dyspnoea (difficult or laboured respiration)
Extrasystoles
Malignant melanoma in situ (early stage of cancer in melanocyte)

60+:

Ageusia (loss of taste functions of the tongue)
Chronic kidney disease
Death
Decreased appetite
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Gout (uric acid crystals building up in the body)
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
Hospitalisation
Insomnia (sleeplessness)
Lethargy (tiredness)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 11 people, 31.43%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 11 people, 31.43%
Tremor (trembling or shaking movements in one or more parts of your body): 4 people, 11.43%
High Blood Pressure: 4 people, 11.43%
Pain: 3 people, 8.57%
Migraine (headache): 3 people, 8.57%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 8.57%
Cardiac Disorder: 3 people, 8.57%
Anaemia (lack of blood): 3 people, 8.57%
Muscle Spasms (muscle contraction): 2 people, 5.71%

* Approximation only. Some reports may have incomplete information.

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