Primidone and Zemplar drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Primidone (primidone) and Zemplar (paricalcitol). Common drug interactions include oedema peripheral among females and confusional state among males.

The phase IV clinical study analyzes what interactions people have when they take Primidone and Zemplar. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Primidone?

Primidone has active ingredients of primidone. It is often used in essential tremor. eHealthMe is studying from 10,474 Primidone users. Check the latest studies of Primidone.

What is Zemplar?

Zemplar has active ingredients of paricalcitol. It is often used in kidney disease. eHealthMe is studying from 15,494 Zemplar users. Check the latest studies of Zemplar.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 04, 2026

12 people who take Primidone and Zemplar together, and have interactions are studied.

Primidone and Zemplar drug interactions.

What are the common drug interactions of Primidone and Zemplar, by gender? *:

female:

Oedema peripheral (superficial swelling)
Bacteraemia (presence of bacteria in the blood)
Decubitus ulcer (a chronic ulcer of the skin caused by prolonged pressure on it)
Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
Abdominal pain upper
Arteriosclerosis (thickening and hardening of arteries)
Atelectasis (partial or complete collapse of the lung)
Cardiac murmur (an heart sound in valve abnormality)
Cardiomyopathy (weakening of the heart muscle)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)

male:

Confusional state
Fall
Chest pain
Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Haematuria (presence of blood in urine)
Pneumonia
Renal failure (kidney dysfunction)
Sepsis (a severe blood infection that can lead to organ failure and death)
Urinary retention (the inability to completely or partially empty the bladder)
Urinary tract infection

What are the common drug interactions of Primidone and Zemplar, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Bacteraemia (presence of bacteria in the blood)
Decubitus ulcer (a chronic ulcer of the skin caused by prolonged pressure on it)
Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
Oedema peripheral (superficial swelling)
Abdominal pain upper
Arteriosclerosis (thickening and hardening of arteries)
Atelectasis (partial or complete collapse of the lung)
Cardiac murmur (an heart sound in valve abnormality)
Cardiomyopathy (weakening of the heart muscle)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)

60+:

Confusional state
Fall
Altered state of consciousness (altered state of mind)
Anaemia (lack of blood)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Blood creatinine increased
Blood glucose increased
Blood pressure increased
Bradycardia (abnormally slow heart action)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)

What are the existing conditions these people have? *

Chest Pain: 6 people, 50.00%
Nuclear Magnetic Resonance Imaging Brain: 5 people, 41.67%
Parkinson's Disease: 1 person, 8.33%
Dyskinesia (abnormality or impairment of voluntary movement): 1 person, 8.33%
Diarrhea: 1 person, 8.33%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

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