Prinivil and Aprepitant drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Prinivil (lisinopril) and Aprepitant (aprepitant). Common drug interactions include systemic lupus erythematosus among females.

The phase IV clinical study analyzes what interactions people have when they take Prinivil and Aprepitant. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Prinivil?

Prinivil has active ingredients of lisinopril. It is often used in high blood pressure. eHealthMe is studying from 20,152 Prinivil users. Check the latest studies of Prinivil.

What is Aprepitant?

Aprepitant has active ingredients of aprepitant. eHealthMe is studying from 6,992 Aprepitant users. Check the latest studies of Aprepitant.



On Jul, 10, 2026

15 people who take Prinivil and Aprepitant together, and have interactions are studied.

Prinivil and Aprepitant drug interactions.

What are the common drug interactions of Prinivil and Aprepitant, by gender? *:

female:

  1. Systemic lupus erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue)
  2. Oedema (fluid collection in tissue)
  3. Fibromyalgia (a long-term condition which causes pain all over the body)
  4. General physical health deterioration (weak health status)
  5. Hand deformity
  6. Helicobacter infection (helicobacter pylori (h. pylori) infects stomach)
  7. Hepatic enzyme increased
  8. Hypersensitivity
  9. Infusion related reaction
  10. Injury

male:

n/a

What are the common drug interactions of Prinivil and Aprepitant, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Pemphigus (any of several acute or chronic skin diseases characterized by groups of itching blisters)
  2. Glossodynia (a burning or painful sensation in the tongue)
  3. Abdominal pain upper
  4. Alopecia (absence of hair from areas of the body)
  5. Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
  6. Breast cancer stage iii
  7. Drug hypersensitivity
  8. Fibromyalgia (a long-term condition which causes pain all over the body)
  9. General physical health deterioration (weak health status)
  10. Hand deformity

50-59:

n/a

60+:

  1. Asthenia (weakness)
  2. Renal failure acute (rapid kidney dysfunction)
  3. Respiratory failure (inadequate gas exchange by the respiratory system)
  4. Small cell lung cancer stage unspecified (lung cancer in unknown stage)
  5. Somnolence (a state of near-sleep, a strong desire for sleep)
  6. Cardiac failure congestive
  7. Diarrhoea
  8. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)

What are the existing conditions these people have? *

  1. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 13 people, 86.67%
  2. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 13 people, 86.67%
  3. Psoriasis (immune-mediated disease that affects the skin): 5 people, 33.33%
  4. Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 2 people, 13.33%
  5. Stress And Anxiety: 2 people, 13.33%
  6. Small Cell Lung Cancer Stage Unspecified (lung cancer in unknown stage): 2 people, 13.33%
  7. Sinusitis (inflammation of sinus): 2 people, 13.33%
  8. Lambert-Eaton Syndrome (this means your immune system mistakenly targets healthy cells and tissues in the body): 2 people, 13.33%
  9. Joint Pain: 2 people, 13.33%
  10. Indigestion: 2 people, 13.33%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Prinivil and Aprepitant:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Prinivil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Aprepitant:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Prinivil and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Aprepitant and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on lisinopril and aprepitant (the active ingredients of Prinivil and Aprepitant, respectively), and Prinivil and Aprepitant (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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