Prinivil and Estraderm drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Prinivil (lisinopril) and Estraderm (estradiol). Common drug interactions include breast cancer among females.

The phase IV clinical study analyzes what interactions people have when they take Prinivil and Estraderm. It is created by eHealthMe based on reports of 29 people who take the same drugs from the FDA, and is updated regularly.

What is Prinivil?

Prinivil has active ingredients of lisinopril. It is often used in high blood pressure. eHealthMe is studying from 20,152 Prinivil users. Check the latest studies of Prinivil.

What is Estraderm?

Estraderm has active ingredients of estradiol. It is often used in hormone replacement therapy. eHealthMe is studying from 3,441 Estraderm users. Check the latest studies of Estraderm.

On Aug, 02, 2026

29 people who take Prinivil and Estraderm together, and have interactions are studied.

Prinivil and Estraderm drug interactions.

What are the common drug interactions of Prinivil and Estraderm, by gender? *:

female:

Breast cancer
Abdominal pain
Tricuspid valve incompetence (inefficient heart valve)
Anaemia (lack of blood)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Osteopenia (a condition where bone mineral density is lower than normal)
Pain
Fatigue (feeling of tiredness)
Headache (pain in head)
Nausea (feeling of having an urge to vomit)

male:

n/a

What are the common drug interactions of Prinivil and Estraderm, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Asthenia (weakness)
Carbohydrate antigen 125 increased
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Colonic polyp (extra part of colon tissue grow in intestine)
Constipation
Dehydration (dryness resulting from the removal of water)
Depression
Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
Dysphagia (a condition in which swallowing is difficult or painful)
Dyspnoea exertional (breathlessness or shortness of breath)

60+:

Breast cancer
Breast mass
Anaemia (lack of blood)
Arterial occlusive disease (slow process through which arteries throughout the body become progressively narrowed and eventually completely blocked)
Breast fibrosis (the thickening and scarring of connective tissue, usually as a result of injury in breast)
Chronic sinusitis (long lasting inflammation of the paranasal sinuses)
Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
Injury
Leukopenia (less number of white blood cells in blood)

What are the existing conditions these people have? *

Menopausal Symptoms: 9 people, 31.03%
Diabetes: 8 people, 27.59%
Menopause (end of monthly cycles in women): 7 people, 24.14%
Malaria (a parasitic disease due to mosquito bite): 6 people, 20.69%
Stress And Anxiety: 4 people, 13.79%
Oedema (fluid collection in tissue): 3 people, 10.34%
Tremor (trembling or shaking movements in one or more parts of your body): 2 people, 6.90%
Rashes (redness): 2 people, 6.90%
Depression: 2 people, 6.90%

* Approximation only. Some reports may have incomplete information.

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