Prinzide and Flomax drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Prinzide (hydrochlorothiazide; lisinopril) and Flomax (tamsulosin hydrochloride). Common drug interactions include application site discomfort among females and weight decreased among males.

The phase IV clinical study analyzes what interactions people have when they take Prinzide and Flomax. It is created by eHealthMe based on reports of 42 people who take the same drugs from the FDA, and is updated regularly.

What is Prinzide?

Prinzide has active ingredients of hydrochlorothiazide; lisinopril. It is often used in high blood pressure. eHealthMe is studying from 2,218 Prinzide users. Check the latest studies of Prinzide.

What is Flomax?

Flomax has active ingredients of tamsulosin hydrochloride. It is often used in enlarged prostate. eHealthMe is studying from 52,865 Flomax users. Check the latest studies of Flomax.

On Jul, 07, 2026

42 people who take Prinzide and Flomax together, and have interactions are studied.

What are the common drug interactions of Prinzide and Flomax, by gender? *:

female:

Application site discomfort
Application site erosion
Purulent discharge (discharge that contains pus)

male:

Weight decreased
Back pain
Prostatic specific antigen increased
Arthralgia (joint pain)
Dysgeusia (disorder of the sense of taste)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Atrial flutter (an abnormal heart rhythm that occurs in the atria of the heart)
Frequent bowel movements
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
Alopecia (absence of hair from areas of the body)

What are the common drug interactions of Prinzide and Flomax, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Blood in stool
Haematocrit decreased
Haemoglobin decreased
Platelet count decreased
Pyrexia (fever)
Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)

50-59:

Application site discomfort
Application site erosion
Chronic kidney disease
Glioblastoma multiforme (most common and deadliest of malignant primary brain tumours in adults)
Purulent discharge (discharge that contains pus)
Renal failure (kidney dysfunction)

60+:

Drug ineffective
Fatigue (feeling of tiredness)
Prostatic specific antigen increased
Arthralgia (joint pain)
Dysgeusia (disorder of the sense of taste)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Atrial flutter (an abnormal heart rhythm that occurs in the atria of the heart)
Frequent bowel movements
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
Alopecia (absence of hair from areas of the body)

What are the existing conditions these people have? *

Prostate Cancer: 9 people, 21.43%
Pain: 6 people, 14.29%
Psoriasis (immune-mediated disease that affects the skin): 5 people, 11.90%
Multiple Myeloma (cancer of the plasma cells): 3 people, 7.14%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 7.14%

* Approximation only. Some reports may have incomplete information.

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