Proamatine and Narcan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Proamatine (midodrine hydrochloride) and Narcan (naloxone hydrochloride). Common drug interactions include sepsis among females and pneumonia among males.

The phase IV clinical study analyzes what interactions people have when they take Proamatine and Narcan. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Proamatine?

Proamatine has active ingredients of midodrine hydrochloride. It is often used in hypotension. eHealthMe is studying from 968 Proamatine users. Check the latest studies of Proamatine.

What is Narcan?

Narcan has active ingredients of naloxone hydrochloride. eHealthMe is studying from 3,687 Narcan users. Check the latest studies of Narcan.

On Jul, 17, 2026

12 people who take Proamatine and Narcan together, and have interactions are studied.

Proamatine and Narcan drug interactions.

What are the common drug interactions of Proamatine and Narcan, by gender? *:

female:

Sepsis (a severe blood infection that can lead to organ failure and death)
Corneal epithelial microcysts (corneal outer covering micro cyst)
Dysphagia (a condition in which swallowing is difficult or painful)
Hospitalisation
Keratopathy (noninflammatory disease of the cornea)
Tremor (trembling or shaking movements in one or more parts of your body)
Vision blurred
Visual acuity reduced (reduced clearness of vision)
Visual impairment
Blood bilirubin increased

male:

Pneumonia
Sepsis (a severe blood infection that can lead to organ failure and death)
Death
Dermatitis exfoliative generalised (inflammatory skin disease with erythema and scaling that affects nearly the entire cutaneous surface)
Dyspnoea (difficult or laboured respiration)
Hypophagia (reduced food intake)
Immune system disorder
Infectious pleural effusion (infectious fluid in the lung)
Leukopenia (less number of white blood cells in blood)
Memory impairment

What are the common drug interactions of Proamatine and Narcan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Streptococcal infection

50-59:

n/a

60+:

Sepsis (a severe blood infection that can lead to organ failure and death)
Pneumonia
Chest pain
Death
Dermatitis exfoliative generalised (inflammatory skin disease with erythema and scaling that affects nearly the entire cutaneous surface)
Dyspnoea (difficult or laboured respiration)
Hypophagia (reduced food intake)
Immune system disorder
Infectious pleural effusion (infectious fluid in the lung)
Leukopenia (less number of white blood cells in blood)

What are the existing conditions these people have? *

Pain: 9 people, 75.00%
Constipation: 7 people, 58.33%
Nausea (feeling of having an urge to vomit): 6 people, 50.00%
Multiple Myeloma (cancer of the plasma cells): 5 people, 41.67%
Fever: 5 people, 41.67%
Rashes (redness): 4 people, 33.33%
Febrile Neutropenia (fever with reduced white blood cells): 4 people, 33.33%
Swallowing Pain Or Burning: 3 people, 25.00%
Stress And Anxiety: 2 people, 16.67%
Sepsis (a severe blood infection that can lead to organ failure and death): 2 people, 16.67%

* Approximation only. Some reports may have incomplete information.

Do you take Proamatine and Narcan?

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