Proamatine and Oxycontin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Proamatine (midodrine hydrochloride) and Oxycontin (oxycodone hydrochloride). Common drug interactions include cardiac disorder among females and arteriosclerosis among males.

The phase IV clinical study analyzes what interactions people have when they take Proamatine and Oxycontin. It is created by eHealthMe based on reports of 37 people who take the same drugs from the FDA, and is updated regularly.

What is Proamatine?

Proamatine has active ingredients of midodrine hydrochloride. It is often used in hypotension. eHealthMe is studying from 968 Proamatine users. Check the latest studies of Proamatine.

What is Oxycontin?

Oxycontin has active ingredients of oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 212,533 Oxycontin users. Check the latest studies of Oxycontin.

On Jul, 16, 2026

37 people who take Proamatine and Oxycontin together, and have interactions are studied.

Proamatine and Oxycontin drug interactions.

What are the common drug interactions of Proamatine and Oxycontin, by gender? *:

female:

Cardiac disorder
Cardiac failure congestive
Cardiomegaly (increased size of heart than normal)
Cardiovascular disorder (heart diseases)
Cellulitis (infection under the skin)
Coagulopathy (blood's ability to clot is impaired)
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Deafness
Dilatation ventricular
Dysgeusia (disorder of the sense of taste)

male:

Arteriosclerosis (thickening and hardening of arteries)
Hepatic failure (liver failure)
Abscess neck (neck abscesses)
Addison's disease (addison's disease, a hormonal disorder disease)
Anaemia of chronic disease
Aneurysm (enlargement of an artery caused by a weakening of the artery wall)
Aortic arteriosclerosis (hardening of the aortic arteries)
Aortic dilatation
Arrhythmia (irregular heartbeat)
Arterial occlusive disease (slow process through which arteries throughout the body become progressively narrowed and eventually completely blocked)

What are the common drug interactions of Proamatine and Oxycontin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Ataxia (loss of full control of bodily movements)
Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)
Dizziness (excl vertigo)
Ecchymosis (a discoloration of the skin resulting from bleeding underneath)
Fall
Haemorrhage (bleeding)
Hypoaesthesia (reduced sense of touch or sensation)
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
Peripheral sensory neuropathy (damage to one or more of your peripheral nerves)
Postural hypotension

50-59:

Cellulitis (infection under the skin)
Coagulopathy (blood's ability to clot is impaired)
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Deafness
Decreased appetite
Dilatation ventricular
Dysgeusia (disorder of the sense of taste)
Dysphagia (a condition in which swallowing is difficult or painful)
Ejection fraction decreased (systolic heart failure)
Enterococcus test positive

60+:

Hepatic failure (liver failure)
Arteriosclerosis (thickening and hardening of arteries)
Constipation
Weight decreased
Hepatitis (inflammation of the liver)
Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)
Abdominal pain
Anxiety
Asthenia (weakness)
Bladder spasm

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 17 people, 45.95%
Hypercalcaemia Of Malignancy (elevated calcium (ca+) level in the blood with cancer): 17 people, 45.95%
Hypercalcaemia (elevated calcium (ca+) level in the blood): 12 people, 32.43%
Nausea (feeling of having an urge to vomit): 3 people, 8.11%
Stress And Anxiety: 2 people, 5.41%
Nausea And Vomiting: 2 people, 5.41%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 5.41%
Depression: 2 people, 5.41%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 2 people, 5.41%

* Approximation only. Some reports may have incomplete information.

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