Probiotic and Boniva drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Probiotic (bacillus coagulans) and Boniva (ibandronate sodium). Common drug interactions include muscle spasms among females and abdominal pain upper among males.

The phase IV clinical study analyzes what interactions people have when they take Probiotic and Boniva. It is created by eHealthMe based on reports of 53 people who take the same drugs from the FDA, and is updated regularly.

What is Probiotic?

Probiotic has active ingredients of bacillus coagulans. It is often used in irritable bowel syndrome. eHealthMe is studying from 22,461 Probiotic users. Check the latest studies of Probiotic.

What is Boniva?

Boniva has active ingredients of ibandronate sodium. It is often used in osteoporosis. eHealthMe is studying from 27,340 Boniva users. Check the latest studies of Boniva.

On Jul, 13, 2026

53 people who take Probiotic and Boniva together, and have interactions are studied.

What are the common drug interactions of Probiotic and Boniva, by gender? *:

female:

Muscle spasms (muscle contraction)
Road traffic accident
Eye pain
Fall
Foot fracture
Nausea (feeling of having an urge to vomit)
Pain in extremity
Peripheral swelling
Arthralgia (joint pain)
Back pain

male:

Abdominal pain upper
Oedema peripheral (superficial swelling)
Rash macular (small, flat red spots)
Abdominal pain
Bowel movement irregularity
Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Urticaria (rash of round, red welts on the skin that itch intensely)

What are the common drug interactions of Probiotic and Boniva, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Contusion (a type of hematoma of tissue in which capillaries)
Depression
Diarrhoea
Fatigue (feeling of tiredness)
Heart rate increased
Heart rate irregular
Hip arthroplasty
Hypertension (high blood pressure)
Ill-defined disorder
Impaired healing

60+:

Fall
Muscle spasms (muscle contraction)
Eye pain
Headache (pain in head)
Nausea (feeling of having an urge to vomit)
Oedema peripheral (superficial swelling)
Pain in jaw
Peripheral swelling
Rash macular (small, flat red spots)
Rectal haemorrhage (bleeding from anus)

What are the existing conditions these people have? *

Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 16 people, 30.19%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 7 people, 13.21%
High Blood Pressure: 7 people, 13.21%
High Blood Cholesterol: 7 people, 13.21%
Multiple Myeloma (cancer of the plasma cells): 5 people, 9.43%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 9.43%
Pain: 4 people, 7.55%
Insomnia (sleeplessness): 3 people, 5.66%
Idiopathic Pulmonary Fibrosis (chronic lung disease): 3 people, 5.66%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 5.66%

* Approximation only. Some reports may have incomplete information.

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