Procardia and Lidoderm drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Procardia (nifedipine) and Lidoderm (lidocaine). Common drug interactions include neurogenic bladder among females and carpal tunnel syndrome among males.

The phase IV clinical study analyzes what interactions people have when they take Procardia and Lidoderm. It is created by eHealthMe based on reports of 54 people who take the same drugs from the FDA, and is updated regularly.

What is Procardia?

Procardia has active ingredients of nifedipine. It is often used in high blood pressure. eHealthMe is studying from 15,151 Procardia users. Check the latest studies of Procardia.

What is Lidoderm?

Lidoderm has active ingredients of lidocaine. It is often used in pain. eHealthMe is studying from 10,524 Lidoderm users. Check the latest studies of Lidoderm.

On Aug, 10, 2026

54 people who take Procardia and Lidoderm together, and have interactions are studied.

Procardia and Lidoderm drug interactions.

What are the common drug interactions of Procardia and Lidoderm, by gender? *:

female:

Neurogenic bladder (the normal function of the bladder is to store and empty urine in a coordinated, controlled fashion)
Peripheral swelling
Restless legs syndrome (a powerful urge to move your legs)
Abdominal discomfort
Abdominal pain upper
Abdominal tenderness
Abscess (pus)
Actinic keratosis (skin disease due to sun exposure)
Affective disorder (mental disorder)
Alopecia (absence of hair from areas of the body)

male:

Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
Chronic kidney disease
Abscess limb (limb infection)
Arthralgia (joint pain)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Blood glucose increased
Body height decreased
Drug ineffective
Fatigue (feeling of tiredness)
Headache (pain in head)

What are the common drug interactions of Procardia and Lidoderm, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Incontinence (lack of moderation or self-control)
Therapeutic response unexpected
Urinary incontinence (inability to control the flow of urine and involuntary urination)

30-39:

n/a

40-49:

Agitation (state of anxiety or nervous excitement)
Alopecia (absence of hair from areas of the body)
Asthenia (weakness)
Blood pressure decreased
Circulatory collapse
Depressed level of consciousness
Diarrhoea haemorrhagic (bloody diarrhoea)
Dyskinesia (abnormality or impairment of voluntary movement)
Formication (a sensation that exactly resembles that of small insects crawling on (or under) the skin)
Homicidal ideation (thoughts about human killing another human)

50-59:

Drooling (drop saliva uncontrollably from the mouth)
Drug hypersensitivity
Glossitis (infection of tongue with soreness)
Hypoacusis (loss of hearing)
Laryngitis (inflammation of the larynx)
Lethargy (tiredness)
Mania (a state of abnormally elevated or irritable mood)
Oral pain
Pyrexia (fever)
Renal injury (kidney injury)

60+:

Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
Colitis ulcerative (inflammation of colon with ulcer)
Abscess limb (limb infection)
Asthenia (weakness)
Blood glucose increased
Body height decreased
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Cyst (a closed sac)
Dementia (madness)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 24 people, 44.44%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 15 people, 27.78%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 14 people, 25.93%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 6 people, 11.11%
Muscle Spasms (muscle contraction): 6 people, 11.11%
Diabetes: 6 people, 11.11%
Back Pain: 6 people, 11.11%
Raynaud's Phenomenon (discoloration of the fingers, toes, and occasionally other areas): 5 people, 9.26%
Migraine (headache): 5 people, 9.26%
Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 4 people, 7.41%

* Approximation only. Some reports may have incomplete information.

Do you take Procardia and Lidoderm?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously