Progesterone and Misoprostol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Progesterone (progesterone) and Misoprostol (misoprostol). Common drug interactions include pain in extremity among females and foetal exposure during pregnancy among males.

The phase IV clinical study analyzes what interactions people have when they take Progesterone and Misoprostol. It is created by eHealthMe based on reports of 46 people who take the same drugs from the FDA, and is updated regularly.

What is Progesterone?

Progesterone has active ingredients of progesterone. It is often used in menopause. eHealthMe is studying from 21,021 Progesterone users. Check the latest studies of Progesterone.

What is Misoprostol?

Misoprostol has active ingredients of misoprostol. It is often used in abortion. eHealthMe is studying from 8,222 Misoprostol users. Check the latest studies of Misoprostol.

On Jul, 29, 2026

46 people who take Progesterone and Misoprostol together, and have interactions are studied.

Progesterone and Misoprostol drug interactions.

What are the common drug interactions of Progesterone and Misoprostol, by gender? *:

female:

Pain in extremity
Pruritus (severe itching of the skin)
Rash
Dehydration (dryness resulting from the removal of water)
Diarrhoea
Infusion related reaction
Vomiting
Abdominal discomfort
Blood pressure increased
Cellulitis (infection under the skin)

male:

Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)
Hypospadias (an abnormal condition in males in which the urethra opens on the under surface of the penis)
Small for dates baby (an unborn baby is growing more slowly and is smaller than most babies are at the same age)

What are the common drug interactions of Progesterone and Misoprostol, by age (0-1 to 60+)? *:

0-1:

Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)
Fistula (an abnormal connection or passageway between two)
Hypospadias (an abnormal condition in males in which the urethra opens on the under surface of the penis)
Small for dates baby (an unborn baby is growing more slowly and is smaller than most babies are at the same age)

2-9:

n/a

10-19:

n/a

20-29:

Progesterone decreased

30-39:

Maternal exposure during pregnancy (use of substance during pregnancy)
Death
Drug abuse
Foetal death (death of foetus)
Haemolysis (breaking open of red blood cells and the release of haemoglobin into the surrounding fluid)
Hellp syndrome (life-threatening pregnancy complication)
Hepatic enzyme increased
Hypertension (high blood pressure)
Maternal exposure before pregnancy (use of substance before pregnancy)
Maternal exposure during delivery (use of substance during pregnancy)

40-49:

Pain
Postpartum haemorrhage (bleeding in woman after she has given birth)
Retained placenta or membranes (placenta in uterus)
Stillbirth (a birth of dead foetus)
Blood sodium decreased
Complex regional pain syndrome (long lasting pain condition most often affecting one of the limbs (arms, legs, hands, or feet))
Palpitations (feelings or sensations that your heart is pounding or racing)
Drug exposure during pregnancy

50-59:

Nausea (feeling of having an urge to vomit)
Dehydration (dryness resulting from the removal of water)
Diarrhoea
Pain
Vomiting
Abdominal discomfort
Arthralgia (joint pain)
Back pain
Blood pressure increased
Bone pain

60+:

Gait disturbance
Pain
Facial bones fracture (bone fracture of face)
Fall
Fatigue (feeling of tiredness)
Hypersomnia (excessive daytime sleepiness (eds))
Injection site erythema (redness at injection site)
Insomnia (sleeplessness)
Nausea (feeling of having an urge to vomit)
Neck pain

What are the existing conditions these people have? *

Labor Induction: 9 people, 19.57%
Immunodeficiency Common Variable: 6 people, 13.04%
Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 6 people, 13.04%
Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 5 people, 10.87%
Pain: 5 people, 10.87%
Stress And Anxiety: 4 people, 8.70%
Nausea (feeling of having an urge to vomit): 4 people, 8.70%
Muscle Spasms (muscle contraction): 4 people, 8.70%
Mood Swings (an extreme or rapid change in mood): 4 people, 8.70%
Migraine (headache): 4 people, 8.70%

* Approximation only. Some reports may have incomplete information.

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