Progesterone and Wakix drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Progesterone (progesterone) and Wakix (pitolisant hydrochloride). Common drug interactions include disability among females.

The phase IV clinical study analyzes what interactions people have when they take Progesterone and Wakix. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.

What is Progesterone?

Progesterone has active ingredients of progesterone. It is often used in menopause. eHealthMe is studying from 21,021 Progesterone users. Check the latest studies of Progesterone.

What is Wakix?

Wakix has active ingredients of pitolisant hydrochloride. eHealthMe is studying from 1,982 Wakix users. Check the latest studies of Wakix.

On Jul, 30, 2026

20 people who take Progesterone and Wakix together, and have interactions are studied.

Progesterone and Wakix drug interactions.

What are the common drug interactions of Progesterone and Wakix, by gender? *:

female:

Disability
Surgery
Hypertension (high blood pressure)
Pain
Retching (strong involuntary effort to vomit)
Weight decreased
Abnormal behaviour
Angina pectoris (chest pain due to ischemia of the heart muscle)
Anxiety
Back pain

male:

n/a

What are the common drug interactions of Progesterone and Wakix, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)
Drug hypersensitivity
Memory impairment
Disability

30-39:

Drug ineffective

40-49:

Nausea (feeling of having an urge to vomit)
Angina pectoris (chest pain due to ischemia of the heart muscle)
Anxiety
Barrett's oesophagus (barrett's oesophagus is a disorder in which the lining of the oesophagus (the tube that carries food from the throat to the stomach) is damaged by stomach acid and changed to a lining similar to that of the stomach)
Blood pressure increased
Breast calcifications (deposits of calcium that can be seen on a mammogram of the breast)
Colitis ulcerative (inflammation of colon with ulcer)
Constipation
Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
Headache (pain in head)

50-59:

Chest pain
Dizziness
Drug ineffective
Enuresis (repeated inability to control urination)
Fluid retention (an abnormal accumulation of fluid in the blood)
Middle insomnia (difficulty returning to sleep after awakening either in the middle of the night)
Musculoskeletal chest pain (pain in chest muscle or nerve or bones)
Nausea (feeling of having an urge to vomit)
Peripheral swelling
Weight increased

60+:

Breast cancer
Fluid retention (an abnormal accumulation of fluid in the blood)
Glaucoma (increased fluid pressure in the eye with vision loss)
Hypertension (high blood pressure)
Neuropathy peripheral (surface nerve damage)
Palpitations (feelings or sensations that your heart is pounding or racing)
Pneumonia
Surgery
Thymoma (a tumour originating from the epithelial cells of the thymus)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 18 people, 90.00%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 14 people, 70.00%
Drowsiness: 13 people, 65.00%
Obstructive Sleep Apnea Syndrome (a sleep disorder that involves cessation or significant decrease in airflow in the presence of breathing effort): 2 people, 10.00%
Migraine (headache): 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

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