Prograf and Calcium lactate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Prograf (tacrolimus) and Calcium lactate (calcium). Common drug interactions include anaemia among females and cerebral haemorrhage among males.

The phase IV clinical study analyzes what interactions people have when they take Prograf and Calcium lactate. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.

What is Prograf?

Prograf has active ingredients of tacrolimus. It is often used in kidney transplant. eHealthMe is studying from 42,230 Prograf users. Check the latest studies of Prograf.

What is Calcium lactate?

Calcium lactate has active ingredients of calcium. eHealthMe is studying from 1,682 Calcium lactate users. Check the latest studies of Calcium lactate.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 25, 2026

23 people who take Prograf and Calcium lactate together, and have interactions are studied.

Prograf and Calcium lactate drug interactions.

What are the common drug interactions of Prograf and Calcium Lactate, by gender? *:

female:

Anaemia (lack of blood)
Drug eruption (adverse drug reaction of the skin)
Nasopharyngitis (inflammation of the nasopharynx)
Altered state of consciousness (altered state of mind)
Blood pressure increased
Pleural effusion (water on the lungs)
Colitis ulcerative (inflammation of colon with ulcer)
Herpes zoster
Iron deficiency anaemia
Renal impairment (severely reduced kidney function)

male:

Cerebral haemorrhage (bleeding within the brain)
International normalised ratio increased
Pneumonia
Respiratory failure (inadequate gas exchange by the respiratory system)
Shunt occlusion (blockage of shunt)
Visual acuity reduced (reduced clearness of vision)
Cytomegalovirus infection
Death
Fall
Femur fracture

What are the common drug interactions of Prograf and Calcium Lactate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Otitis media (inflammation of the middle ear)
Paralysis
Pulmonary oedema (fluid accumulation in the lungs)
Sinusitis (inflammation of sinus)
Spinal cord infarction (tissue damage of spinal cord due to lack of blood supply)
Spinal shock (low blood pressure due to spinal condition /injury)
Cerebral haemorrhage (bleeding within the brain)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Haemorrhagic cerebral infarction (brain stroke with bleeding)
Haemorrhagic infarction (stroke caused by the rupture of a blood vessel in the brain)

10-19:

n/a

20-29:

Colitis ulcerative (inflammation of colon with ulcer)
Drug eruption (adverse drug reaction of the skin)
Iron deficiency anaemia
Nasopharyngitis (inflammation of the nasopharynx)
Renal impairment (severely reduced kidney function)
Herpes zoster
Osteonecrosis (death of bone)
Pruritus (severe itching of the skin)
Vitreous floaters (spots before the eyes)
Upper respiratory tract infection

30-39:

Cystitis bacterial (inflammation of the wall of the bladder by bacteria escherichia coli)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Diabetic nephropathy (diabetic kidney disease)
Fall
Femur fracture
Gangrene (body tissue dies)
Hallucination (an experience involving the perception of something not present)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Wound infection staphylococcal

40-49:

Anaemia (lack of blood)
Drug eruption (adverse drug reaction of the skin)
Herpes zoster
Nasopharyngitis (inflammation of the nasopharynx)

50-59:

Blood potassium increased
Cytomegalovirus infection
Gangrene (body tissue dies)
Hyperuricaemia (level of uric acid in the blood that is abnormally high)
Lymphocyte count decreased
Respiratory failure (inadequate gas exchange by the respiratory system)
Shunt occlusion (blockage of shunt)

60+:

Altered state of consciousness (altered state of mind)
Anaemia (lack of blood)
International normalised ratio increased
Malaise (a feeling of general discomfort or uneasiness)
Death
Macular oedema (fluid and protein deposits collect on or under the macula of the eye (a yellow central area of the retina) and causes it to thicken)
Visual acuity reduced (reduced clearness of vision)
Blood pressure increased
Pleural effusion (water on the lungs)
Pneumonia

What are the existing conditions these people have? *

Osteoporosis (bones weak and more likely to break): 12 people, 52.17%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 7 people, 30.43%
Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 4 people, 17.39%
Hyperlipidaemia (presence of excess lipids in the blood): 3 people, 13.04%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 13.04%
Folate Deficiency (lack of folic acid): 3 people, 13.04%
Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 2 people, 8.70%
Takayasu's Arteritis (an inflammation of the aorta -- the artery that carries blood from the heart to the rest of the body): 2 people, 8.70%
Insomnia (sleeplessness): 2 people, 8.70%
Hyperkalemia (damage to or disease of the kidney): 2 people, 8.70%

* Approximation only. Some reports may have incomplete information.

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