Prograf and Hizentra drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Prograf (tacrolimus) and Hizentra (human immunoglobulin g). Common drug interactions include influenza among females and rash among males.

The phase IV clinical study analyzes what interactions people have when they take Prograf and Hizentra. It is created by eHealthMe based on reports of 50 people who take the same drugs from the FDA, and is updated regularly.

What is Prograf?

Prograf has active ingredients of tacrolimus. It is often used in kidney transplant. eHealthMe is studying from 42,230 Prograf users. Check the latest studies of Prograf.

What is Hizentra?

Hizentra has active ingredients of human immunoglobulin g. eHealthMe is studying from 23,666 Hizentra users. Check the latest studies of Hizentra.

On Jul, 12, 2026

50 people who take Prograf and Hizentra together, and have interactions are studied.

What are the common drug interactions of Prograf and Hizentra, by gender? *:

female:

Influenza
Pain
Lung transplant rejection (failure of lung transplant)
Herpes zoster
Loss of consciousness
Pyrexia (fever)
Death
Administration site pain
Ear infection
Infusion site bruising

male:

Rash
Drug eruption (adverse drug reaction of the skin)
Pneumonia
Bacterial infection
Headache (pain in head)
Staphylococcal infection (an infection with staphylococcus bacteria)
Upper respiratory tract inflammation
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Behcet's syndrome (involves inflammation of the blood vessels)
Erythema nodosum (skin inflammation that results in reddish, painful, tender lumps most commonly located in the front of the legs below)

What are the common drug interactions of Prograf and Hizentra, by age (0-1 to 60+)? *:

0-1:

Abdominal abscess (collection of pus in abdomen)
Blood beta-d-glucan increased
Dehydration (dryness resulting from the removal of water)
Infection
Renal failure (kidney dysfunction)
Transplant rejection (a transplant material is not worked)

2-9:

Respiratory tract infection viral
Croup infectious (a loud cough that resembles the barking of a seal and difficulty breathing can transfer to other)
Liver transplant rejection (failure of liver transplant)
Parainfluenzae virus infection
Infection
Interstitial lung disease

10-19:

Arthritis (form of joint disorder that involves inflammation of one or more joints)
Behcet's syndrome (involves inflammation of the blood vessels)
Erythema nodosum (skin inflammation that results in reddish, painful, tender lumps most commonly located in the front of the legs below)
Headache (pain in head)
Inflammatory marker increased
Mouth ulceration (mouth ulcers)
Pyrexia (fever)
Rash
Scrotal ulcer
Thrombophlebitis (swelling (inflammation) of a vein caused by a blood clot)

20-29:

Bacterial infection
Pneumonia
Fall
Respiratory depression (respiration has a rate below 12 breaths)
Upper limb fracture
Wound

30-39:

Lung transplant rejection (failure of lung transplant)
Obliterative bronchiolitis (bronchiolar inflammation)

40-49:

Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
Pulmonary fibrosis (formation or development of excess fibrous connective tissue (fibrosis) in the lungs)

50-59:

Renal failure (kidney dysfunction)
Rhinovirus infection

60+:

Anaphylactic reaction (serious allergic reaction)
Drug eruption (adverse drug reaction of the skin)
Rash
Pain
Herpes zoster
Loss of consciousness
Pyrexia (fever)
Tenderness (pain or discomfort when an affected area is touched)
Death
Low cardiac output syndrome (decreased cardiac output)

What are the existing conditions these people have? *

Immunodeficiency Common Variable: 19 people, 38.00%
Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection): 15 people, 30.00%
Secondary Immunodeficiency (lack of immunity due to some disease): 8 people, 16.00%
Chronic Inflammatory Demyelinating Polyradiculoneuropathy (long lasting infection of nerves outside brain and spinal cord): 4 people, 8.00%
Prostate Cancer: 3 people, 6.00%
Osteoporosis (bones weak and more likely to break): 3 people, 6.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 6.00%
Enlarged Prostate: 3 people, 6.00%
Dyslipidaemia (abnormal amount of lipids): 3 people, 6.00%
Diabetes: 3 people, 6.00%

* Approximation only. Some reports may have incomplete information.

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