Prograf and Pamelor drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Prograf (tacrolimus) and Pamelor (nortriptyline hydrochloride). Common drug interactions include memory impairment among females and abdominal pain upper among males.

The phase IV clinical study analyzes what interactions people have when they take Prograf and Pamelor. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Prograf?

Prograf has active ingredients of tacrolimus. It is often used in kidney transplant. eHealthMe is studying from 42,230 Prograf users. Check the latest studies of Prograf.

What is Pamelor?

Pamelor has active ingredients of nortriptyline hydrochloride. It is often used in migraine. eHealthMe is studying from 4,069 Pamelor users. Check the latest studies of Pamelor.

On Jul, 11, 2026

14 people who take Prograf and Pamelor together, and have interactions are studied.

What are the common drug interactions of Prograf and Pamelor, by gender? *:

female:

Memory impairment
Anxiety
Blood creatinine increased
Blood potassium decreased
Blood pressure fluctuation
Dyspepsia (indigestion)
Fatigue (feeling of tiredness)
Fluid retention (an abnormal accumulation of fluid in the blood)
Foot fracture
Hypertension (high blood pressure)

male:

Abdominal pain upper
Arthritis bacterial (form of joint disorder that involves inflammation of one or more joints due to bacterial infection)
Osteoporosis (bones weak and more likely to break)
Pneumonitis (inflammation of the walls of the alveoli in the lungs)
Pseudomonas infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa)
Renal failure chronic (long lasting kidney dysfunction)
Respiratory acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease)
Sepsis (a severe blood infection that can lead to organ failure and death)
Transplant failure (transplantation failed to meet outcome)
Tremor (trembling or shaking movements in one or more parts of your body)

What are the common drug interactions of Prograf and Pamelor, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Leukaemia recurrent (repeat cancer of bone marrow or blood cells)

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Cardiac failure
Catheter site pain
Diaphragmatic paralysis (acquired dysfunction of the phrenic nerve)
Myoclonus (a brief, involuntary twitching of a muscle or a group of muscles)
Obliterative bronchiolitis (bronchiolar inflammation)
Osteonecrosis (death of bone)
Osteoporosis (bones weak and more likely to break)
Pneumonia
Pneumonitis (inflammation of the walls of the alveoli in the lungs)
Pseudomonas infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa)

60+:

Foot deformity (functional disability of foot)
Insomnia (sleeplessness)
Memory impairment
Mobility decreased (ability to move is reduced)
Myalgia (muscle pain)
Pain
Stress

What are the existing conditions these people have? *

Pain: 5 people, 35.71%
Constipation: 3 people, 21.43%
Nausea (feeling of having an urge to vomit): 3 people, 21.43%
Abdominal Pain: 2 people, 14.29%
Blood Potassium Decreased: 2 people, 14.29%
Focal Segmental Glomerulosclerosis (scar tissue that forms in parts of the kidney called glomeruli): 2 people, 14.29%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 14.29%
Gastrointestinal Disorder (functional problems of gastrointestinal tract): 2 people, 14.29%
Swelling: 2 people, 14.29%
High Blood Cholesterol: 2 people, 14.29%

* Approximation only. Some reports may have incomplete information.

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