Prograf and Ribasphere drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Prograf (tacrolimus) and Ribasphere (ribavirin). Common drug interactions include diverticulitis among females and death among males.
The phase IV clinical study analyzes what interactions people have when they take Prograf and Ribasphere. It is created by eHealthMe based on reports of 28 people who take the same drugs from the FDA, and is updated regularly.
What is Prograf?
Prograf has active ingredients of tacrolimus. It is often used in kidney transplant. eHealthMe is studying from 42,230 Prograf users. Check the latest studies of Prograf.
What is Ribasphere?
Ribasphere has active ingredients of ribavirin. It is often used in hepatitis c. eHealthMe is studying from 9,336 Ribasphere users. Check the latest studies of Ribasphere.
28 people who take Prograf and Ribasphere together, and have interactions are studied.

What are the common drug interactions of Prograf and Ribasphere, by gender? *:
female:
- Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
- Asthenia (weakness)
- Rectal haemorrhage (bleeding from anus)
- Anaemia (lack of blood)
- Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
- Diarrhoea
- Dyspnoea (difficult or laboured respiration)
- Fatigue (feeling of tiredness)
- Oedema peripheral (superficial swelling)
- Abdominal distension
male:
- Death
- Dyspepsia (indigestion)
- Dyspnoea (difficult or laboured respiration)
- Haemoglobin decreased
- Memory impairment
- Rash
- Renal failure (kidney dysfunction)
- Tremor (trembling or shaking movements in one or more parts of your body)
- Abdominal discomfort
- Abdominal pain
What are the common drug interactions of Prograf and Ribasphere, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Hallucination, visual (seeing things that aren't there)
- Memory impairment
- Red blood cell count decreased
- White blood cell count decreased
40-49:
n/a
50-59:
- Death
- Dyspepsia (indigestion)
- Asthenia (weakness)
- Blood glucose increased
- Diarrhoea
- Dyspnoea (difficult or laboured respiration)
- Fatigue (feeling of tiredness)
- Headache (pain in head)
- Nausea (feeling of having an urge to vomit)
- Rash
60+:
- Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
- Asthenia (weakness)
- Disease recurrence
- Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
- Mood swings (an extreme or rapid change in mood)
- Nausea (feeling of having an urge to vomit)
- Vomiting
- White blood cell count decreased
- Fatigue (feeling of tiredness)
- Rectal haemorrhage (bleeding from anus)
What are the existing conditions these people have? *
- Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 10.71%
* Approximation only. Some reports may have incomplete information.
Do you take Prograf and Ribasphere?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Prograf (42,230 reports)
- Ribasphere (9,336 reports)
Browse all drug interactions of Prograf and Ribasphere:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Prograf:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Ribasphere:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Prograf and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Ribasphere and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Lin SY, Lin CL, Ju SW, Wang IK, Lin CC, Lin CH, Hsu WH, Liang JA, "Increasing risk of cataract in HCV patients receiving anti-HCV therapy: A nationwide cohort study", PloS one, 2017 Mar .
- Lin SY, Lin CL, Ju SW, Wang IK, Lin CC, Lin CH, Hsu WH, Liang JA, "Increasing risk of cataract in HCV patients receiving anti-HCV therapy: A nationwide cohort study", PloS one, 2017 Mar .
How the study uses the data?
The study uses data from the FDA. It is based on tacrolimus and ribavirin (the active ingredients of Prograf and Ribasphere, respectively), and Prograf and Ribasphere (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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