Prolensa and Doxycycline drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Prolensa (bromfenac sodium) and Doxycycline (doxycycline hyclate). Common drug interactions include chronic kidney disease among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Prolensa and Doxycycline. It is created by eHealthMe based on reports of 31 people who take the same drugs from the FDA, and is updated regularly.

What is Prolensa?

Prolensa has active ingredients of bromfenac sodium. eHealthMe is studying from 1,170 Prolensa users. Check the latest studies of Prolensa.

What is Doxycycline?

Doxycycline has active ingredients of doxycycline hyclate. It is often used in acne. eHealthMe is studying from 60,866 Doxycycline users. Check the latest studies of Doxycycline.



On Jul, 08, 2026

31 people who take Prolensa and Doxycycline together, and have interactions are studied.

Prolensa and Doxycycline drug interactions.

What are the common drug interactions of Prolensa and Doxycycline, by gender? *:

female:

  1. Chronic kidney disease
  2. Renal injury (kidney injury)
  3. Asthenia (weakness)
  4. Disability
  5. Extrasystoles
  6. Fall
  7. Muscle fatigue (a condition in which muscles cannot exert their normal force)
  8. Myalgia (muscle pain)
  9. Renal failure (kidney dysfunction)
  10. Accident

male:

  1. Chronic kidney disease
  2. Renal failure (kidney dysfunction)
  3. Nephrogenic anaemia (anaemia due to kidney disease)
  4. Neuropathy peripheral (surface nerve damage)
  5. Platelet count decreased
  6. Protein total increased
  7. Renal injury (kidney injury)
  8. Retinal detachment (a disorder of the eye in which the retina peels away from its underlying layer of support tissue)
  9. Therapeutic response decreased (less preventive response)
  10. Ulcerative keratitis (ulcerative inflammation of the cornea)

What are the common drug interactions of Prolensa and Doxycycline, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Chronic kidney disease
  2. Renal failure (kidney dysfunction)
  3. Renal injury (kidney injury)
  4. Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
  5. Gastric ulcer (stomach ulcer)
  6. Renal tubular acidosis (medical condition that involves an accumulation of acid in the body due to a failure of the kidneys)
  7. Suicidal ideation
  8. Depression
  9. Diarrhoea
  10. Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus)

60+:

  1. Chronic kidney disease
  2. Renal failure (kidney dysfunction)
  3. Muscle fatigue (a condition in which muscles cannot exert their normal force)
  4. Myalgia (muscle pain)
  5. Accident
  6. Blepharitis (chronic inflammation of the eyelid)
  7. Coagulopathy (blood's ability to clot is impaired)
  8. Cystitis (inflammation of the wall of the bladder)
  9. Erythema (redness of the skin)
  10. Fall

What are the existing conditions these people have? *

  1. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 12 people, 38.71%
  2. Pain: 10 people, 32.26%
  3. High Blood Cholesterol: 9 people, 29.03%
  4. High Blood Pressure: 8 people, 25.81%
  5. Multiple Myeloma (cancer of the plasma cells): 7 people, 22.58%
  6. Cardiac Disorder: 7 people, 22.58%
  7. Infection: 6 people, 19.35%
  8. Depression: 5 people, 16.13%
  9. Stress And Anxiety: 5 people, 16.13%
  10. Hypersensitivity: 4 people, 12.90%

* Approximation only. Some reports may have incomplete information.

Do you take Prolensa and Doxycycline?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Prolensa and Doxycycline:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Prolensa:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Doxycycline:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Prolensa and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Doxycycline and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on bromfenac sodium and doxycycline hyclate (the active ingredients of Prolensa and Doxycycline, respectively), and Prolensa and Doxycycline (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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