Proleukin and Meropenem drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Proleukin (aldesleukin) and Meropenem (meropenem). Common drug interactions include blood bilirubin increased among females and cytokine release syndrome among males.

The phase IV clinical study analyzes what interactions people have when they take Proleukin and Meropenem. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.

What is Proleukin?

Proleukin has active ingredients of aldesleukin. eHealthMe is studying from 1,865 Proleukin users. Check the latest studies of Proleukin.

What is Meropenem?

Meropenem has active ingredients of meropenem. eHealthMe is studying from 33,295 Meropenem users. Check the latest studies of Meropenem.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 18, 2026

26 people who take Proleukin and Meropenem together, and have interactions are studied.

Proleukin and Meropenem drug interactions.

What are the common drug interactions of Proleukin and Meropenem, by gender? *:

female:

Blood bilirubin increased
Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
Neutropenic sepsis (whole body infection is caused by a condition in which the number of white blood cells (called neutrophils) in the blood is low. neutrophils help the body to fight infection)
Thrombocytopenia (decrease of platelets in blood)
Diarrhoea
Febrile neutropenia (fever with reduced white blood cells)
Pyrexia (fever)
Platelet count decreased
Pulmonary oedema (fluid accumulation in the lungs)
Respiratory failure (inadequate gas exchange by the respiratory system)

male:

Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
Abdominal distension
Cyanosis (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails)
Depression
Drug hypersensitivity
Dyspnoea (difficult or laboured respiration)
Large intestine perforation (hole in large intestine)
Nausea (feeling of having an urge to vomit)
Neutropenic sepsis (whole body infection is caused by a condition in which the number of white blood cells (called neutrophils) in the blood is low. neutrophils help the body to fight infection)
Peripheral ischaemia (impaired circulation to an extremity)

What are the common drug interactions of Proleukin and Meropenem, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Diarrhoea
Febrile neutropenia (fever with reduced white blood cells)
Pyrexia (fever)
Platelet count decreased
Pancreatic carcinoma metastatic (pancreatic cancer- metastatic)
Tumour pain
Abdominal pain
Pulmonary embolism (blockage of the main artery of the lung)
Respiratory failure (inadequate gas exchange by the respiratory system)
Blood bicarbonate decreased

50-59:

Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Respiratory failure (inadequate gas exchange by the respiratory system)
Aortic thrombosis (formation of a blood clot inside aorta)
Peripheral ischaemia (impaired circulation to an extremity)

60+:

Pulmonary oedema (fluid accumulation in the lungs)
Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)

What are the existing conditions these people have? *

Pancreatic Carcinoma Metastatic (pancreatic cancer- metastatic): 14 people, 53.85%
Infection: 12 people, 46.15%
Neutropenic Sepsis (whole body infection is caused by a condition in which the number of white blood cells (called neutrophils) in the blood is low. neutrophils help the body to fight infection): 11 people, 42.31%
Metastatic Malignant Melanoma (spreadable cancer tumour of melanine): 7 people, 26.92%
Hypotension (abnormally low blood pressure): 5 people, 19.23%
Nausea (feeling of having an urge to vomit): 3 people, 11.54%
Capillary Leak Syndrome (capillary leaks plasma): 3 people, 11.54%
Device Related Infection: 2 people, 7.69%
Arrhythmias (irregular heartbeat): 2 people, 7.69%
Constipation: 2 people, 7.69%

* Approximation only. Some reports may have incomplete information.

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