Proleukin and Reglan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Proleukin (aldesleukin) and Reglan (metoclopramide hydrochloride). Common drug interactions include t-cell depletion among females and sepsis among males.

The phase IV clinical study analyzes what interactions people have when they take Proleukin and Reglan. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Proleukin?

Proleukin has active ingredients of aldesleukin. eHealthMe is studying from 1,865 Proleukin users. Check the latest studies of Proleukin.

What is Reglan?

Reglan has active ingredients of metoclopramide hydrochloride. It is often used in gastroparesis. eHealthMe is studying from 29,455 Reglan users. Check the latest studies of Reglan.

On Jul, 15, 2026

19 people who take Proleukin and Reglan together, and have interactions are studied.

What are the common drug interactions of Proleukin and Reglan, by gender? *:

female:

T-cell depletion (less supply of t-cell by bone marrow)
Urinary tract infection
Vaginal haemorrhage (vaginal bleeding)
Vaginitis (inflammation of the vagina)
Vertigo
White blood cell count increased
Vomiting
Hypotension (abnormally low blood pressure)
Pyrexia (fever)
Sepsis (a severe blood infection that can lead to organ failure and death)

male:

Sepsis (a severe blood infection that can lead to organ failure and death)
Fatigue (feeling of tiredness)
Platelet count decreased
Pyrexia (fever)
Renal failure (kidney dysfunction)
Respiratory tract infection
Streptococcal infection
White blood cell count decreased
Abdominal discomfort
Alanine aminotransferase increased

What are the common drug interactions of Proleukin and Reglan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Hypokalaemia (low potassium)
Hypophosphataemia (electrolyte disturbance in which there is an abnormally low level of phosphate in the blood)

10-19:

n/a

20-29:

Hypokalaemia (low potassium)
Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)
Malaise (a feeling of general discomfort or uneasiness)
Pyrexia (fever)
Rigors (an episode of shaking or exaggerated shivering)
Sepsis (a severe blood infection that can lead to organ failure and death)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Tenderness (pain or discomfort when an affected area is touched)
Vomiting
White blood cell count decreased

30-39:

Abdominal tenderness
Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
Drug ineffective
Drug intolerance (drug sensitivity)
Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body)
Leukaemia recurrent (repeat cancer of bone marrow or blood cells)
T-cell depletion (less supply of t-cell by bone marrow)
Urinary tract infection
Vaginitis (inflammation of the vagina)

40-49:

Catheter related infection
Coma (state of unconsciousness lasting more than six hours)
Fatigue (feeling of tiredness)
Groin abscess (pus in groin)
Lethargy (tiredness)
Renal failure (kidney dysfunction)
Sepsis (a severe blood infection that can lead to organ failure and death)
Streptococcal infection
Pulmonary embolism (blockage of the main artery of the lung)
Respiratory failure (inadequate gas exchange by the respiratory system)

50-59:

Arrhythmia (irregular heartbeat)
Capillary leak syndrome (capillary leaks plasma)
Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
Diarrhoea
Heart rate decreased
Hepatic failure (liver failure)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Hypotension (abnormally low blood pressure)
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Hypoxia (low oxygen in tissues)

60+:

Pyrexia (fever)
Sepsis (a severe blood infection that can lead to organ failure and death)
Haemoglobin decreased
Klebsiella bacteraemia (klebsiella bacteria in blood after infection to lungs)
Platelet count decreased
Respiratory tract infection
Syncope (loss of consciousness with an inability to maintain postural tone)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Vomiting
White blood cell count decreased

What are the existing conditions these people have? *

Nausea (feeling of having an urge to vomit): 5 people, 26.32%
Malignant Melanoma (skin cancer rises from melancytes): 3 people, 15.79%
Malignant Melanoma Stage Iii (cancer has spread to one or more lymph nodes): 2 people, 10.53%
Renal Cancer Metastatic (cancer of kidney spreads to other part): 2 people, 10.53%
Weight Increased: 1 person, 5.26%
Diabetes: 1 person, 5.26%
Hypokalemia (low potassium): 1 person, 5.26%
Hypoglycemia (low blood sugar): 1 person, 5.26%
Hypocalcaemia (levels of calcium in blood serum are abnormally low): 1 person, 5.26%
Herpes Simplex (herpes simplex is a common viral infection): 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

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