Prolia and Everolimus drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Prolia (denosumab) and Everolimus (everolimus). Common drug interactions include disease progression among females and cerebrovascular accident among males.

The phase IV clinical study analyzes what interactions people have when they take Prolia and Everolimus. It is created by eHealthMe based on reports of 32 people who take the same drugs from the FDA, and is updated regularly.

What is Prolia?

Prolia has active ingredients of denosumab. It is often used in osteoporosis. eHealthMe is studying from 151,388 Prolia users. Check the latest studies of Prolia.

What is Everolimus?

Everolimus has active ingredients of everolimus. eHealthMe is studying from 16,228 Everolimus users. Check the latest studies of Everolimus.

On Jul, 20, 2026

32 people who take Prolia and Everolimus together, and have interactions are studied.

Prolia and Everolimus drug interactions.

What are the common drug interactions of Prolia and Everolimus, by gender? *:

female:

Disease progression
Cough
Metastases to bone (cancer spreads to bone)
Pneumonitis (inflammation of the walls of the alveoli in the lungs)
Bone disorder
Breast cancer female
Lymphadenopathy mediastinal (an enlargement of the lymph nodes in the part of the chest that separates the lungs)
Metastases to lymph nodes (cancer spreads to lymph node)
Pericardial effusion (fluid around the heart)
Pleural effusion (water on the lungs)

male:

Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Pancreatic neuroendocrine tumour metastatic
Prostatomegaly (enlargement of the prostate)
Vomiting
Rash
Bradyphrenia (neurological term referring to the slowness of thought common to many disorders of the brain)
Blood parathyroid hormone increased
Constipation
Hypercalcaemia of malignancy (elevated calcium (ca+) level in the blood with cancer)

What are the common drug interactions of Prolia and Everolimus, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Renal disorder (kidney disease)
Throat irritation
Bone disorder
Breast cancer female
Cough
Disease progression
Lymphadenopathy mediastinal (an enlargement of the lymph nodes in the part of the chest that separates the lungs)
Metastases to bone (cancer spreads to bone)
Metastases to lymph nodes (cancer spreads to lymph node)
Pericardial effusion (fluid around the heart)

50-59:

Blindness
Blood parathyroid hormone increased
Blood pressure increased
Constipation
Headache (pain in head)
Hypercalcaemia of malignancy (elevated calcium (ca+) level in the blood with cancer)
Hypocalcaemia (levels of calcium in blood serum are abnormally low)
Nausea (feeling of having an urge to vomit)
Neoplasm progression (growth of tumour)
Nephrolithiasis (calculi in the kidneys)

60+:

Rash
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Burning sensation
Adverse drug reaction
Anaemia (lack of blood)
Anxiety
Asthenia (weakness)
Back pain
Bedridden
Blood pressure decreased

What are the existing conditions these people have? *

Breast Cancer Female: 3 people, 9.38%
Breast Cancer: 3 people, 9.38%
Osteoporosis Post-Menopausal (weak bone with possibility to break after stopped menstrual cycles): 2 people, 6.25%
Osteopenia (a condition where bone mineral density is lower than normal): 2 people, 6.25%

* Approximation only. Some reports may have incomplete information.

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