Prolia and Gemfibrozil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Prolia (denosumab) and Gemfibrozil (gemfibrozil). Common drug interactions include faeces hard among females and abdominal distension among males.

The phase IV clinical study analyzes what interactions people have when they take Prolia and Gemfibrozil. It is created by eHealthMe based on reports of 42 people who take the same drugs from the FDA, and is updated regularly.

What is Prolia?

Prolia has active ingredients of denosumab. It is often used in osteoporosis. eHealthMe is studying from 151,388 Prolia users. Check the latest studies of Prolia.

What is Gemfibrozil?

Gemfibrozil has active ingredients of gemfibrozil. It is often used in high blood cholesterol. eHealthMe is studying from 18,213 Gemfibrozil users. Check the latest studies of Gemfibrozil.

On Jul, 21, 2026

42 people who take Prolia and Gemfibrozil together, and have interactions are studied.

Prolia and Gemfibrozil drug interactions.

What are the common drug interactions of Prolia and Gemfibrozil, by gender? *:

female:

Faeces hard
Fall
Fatigue (feeling of tiredness)
Full blood count decreased
Fungal infection
Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)
Gastrointestinal oedema (excessive build-up of fluid in the gastrointestinal tract tissues)
Groin pain
Hallucination (an experience involving the perception of something not present)
Hyperparathyroidism (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium)

male:

Abdominal distension
Nausea (feeling of having an urge to vomit)
Cardiac arrest
Chest discomfort
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Compartment syndrome (painful condition that occurs when pressure within the muscles builds to dangerous levels)
Confusional state
Constipation
Cutaneous vasculitis (an inflammatory process affecting the vessel wall that leads to its damage)
Decreased appetite

What are the common drug interactions of Prolia and Gemfibrozil, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Oropharyngeal pain
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Pain
Pruritus (severe itching of the skin)
Systemic lupus erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue)
Upper respiratory tract infection
Urinary incontinence (inability to control the flow of urine and involuntary urination)
Urticaria (rash of round, red welts on the skin that itch intensely)
Arthralgia (joint pain)
Dehydration (dryness resulting from the removal of water)

60+:

Pain
Arthralgia (joint pain)
Diarrhoea
Eructation (release of gas from the digestive tract)
Erythema (redness of the skin)
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Haemorrhage (bleeding)
Hypocalcaemia (levels of calcium in blood serum are abnormally low)
Hypophosphataemia (electrolyte disturbance in which there is an abnormally low level of phosphate in the blood)
Influenza like illness

What are the existing conditions these people have? *

Osteoporosis Post-Menopausal (weak bone with possibility to break after stopped menstrual cycles): 11 people, 26.19%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 5 people, 11.90%
Vitamin D Decreased: 3 people, 7.14%
Prostate Cancer: 3 people, 7.14%
Multiple Myeloma (cancer of the plasma cells): 3 people, 7.14%
Immunodeficiency Common Variable: 3 people, 7.14%
Blood Phosphorus Increased: 3 people, 7.14%

* Approximation only. Some reports may have incomplete information.

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