Prolia and Lenalidomide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Prolia (denosumab) and Lenalidomide (lenalidomide). Common drug interactions include atrial fibrillation among females and arthritis among males.

The phase IV clinical study analyzes what interactions people have when they take Prolia and Lenalidomide. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.

What is Prolia?

Prolia has active ingredients of denosumab. It is often used in osteoporosis. eHealthMe is studying from 151,388 Prolia users. Check the latest studies of Prolia.

What is Lenalidomide?

Lenalidomide has active ingredients of lenalidomide. eHealthMe is studying from 52,881 Lenalidomide users. Check the latest studies of Lenalidomide.

On Aug, 03, 2026

26 people who take Prolia and Lenalidomide together, and have interactions are studied.

Prolia and Lenalidomide drug interactions.

What are the common drug interactions of Prolia and Lenalidomide, by gender? *:

female:

Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Anaemia (lack of blood)
Asthma
Helicobacter gastritis (inflammation of the inner lining of the stomach caused by helicobacter pylori (h. pylori) a bacterium)
Hyperviscosity syndrome (a condition in which blood is not able to flow freely through your arteries)
Plasma cell myeloma (cancer that begins in plasma cells)
Pneumonia pneumococcal (pneumococcal pneumonia is a common but serious infection and inflammation of the lungs)
Pulmonary oedema (fluid accumulation in the lungs)
Respiratory tract infection
Tumour lysis syndrome (a group of metabolic complications that can occur after treatment of cancer, these complications are caused by the breakdown products of dying cancer cells)

male:

Arthritis (form of joint disorder that involves inflammation of one or more joints)
Cardiac failure congestive
Seasonal allergy (allergic condition due to certain season)
Cough
Limb discomfort (discomfort in leg)
Neoplasm malignant (cancer tumour)
Oropharyngeal pain
Pain
Protein total increased
Respiratory distress (difficulty in breathing)

What are the common drug interactions of Prolia and Lenalidomide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Respiratory tract infection
Beta haemolytic streptococcal infection (infection with streptococcus pyogenes, a beta-haemolytic bacterium cause mild to moderately severe respiratory tract, skin, and soft tissue)
Diarrhoea
Hyperkalaemia (damage to or disease of the kidney)
Oedema peripheral (superficial swelling)
Metastatic neoplasm (spreadable cancer tumour)
Neutropenic sepsis (whole body infection is caused by a condition in which the number of white blood cells (called neutrophils) in the blood is low. neutrophils help the body to fight infection)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Cardiac failure congestive

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 20 people, 76.92%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 4 people, 15.38%
Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 2 people, 7.69%

* Approximation only. Some reports may have incomplete information.

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