Prolia and Panadol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Prolia (denosumab) and Panadol (acetaminophen). Common drug interactions include myelodysplastic syndrome among females and device occlusion among males.

The phase IV clinical study analyzes what interactions people have when they take Prolia and Panadol. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Prolia?

Prolia has active ingredients of denosumab. It is often used in osteoporosis. eHealthMe is studying from 151,388 Prolia users. Check the latest studies of Prolia.

What is Panadol?

Panadol has active ingredients of acetaminophen. eHealthMe is studying from 607 Panadol users. Check the latest studies of Panadol.

On Jul, 14, 2026

19 people who take Prolia and Panadol together, and have interactions are studied.

What are the common drug interactions of Prolia and Panadol, by gender? *:

female:

Myelodysplastic syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged)
Rectal haemorrhage (bleeding from anus)
Arthralgia (joint pain)
Cough
Myalgia (muscle pain)
Pain in extremity
Spinal compression fracture (fracture due to spinal compression on bone)
Nasopharyngitis (inflammation of the nasopharynx)
Abdominal distension
Abdominal pain upper

male:

Device occlusion
Fall
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
General symptom
Increased upper airway secretion
Urinary tract inflammation

What are the common drug interactions of Prolia and Panadol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

Blood creatinine increased
Fluid retention (an abnormal accumulation of fluid in the blood)
Spinal compression fracture (fracture due to spinal compression on bone)
Nasopharyngitis (inflammation of the nasopharynx)
Abdominal distension
Abdominal pain upper
Alopecia (absence of hair from areas of the body)
Blood calcium decreased
Blood cholesterol increased
Blood glucose increased

What are the existing conditions these people have? *

Hypersensitivity: 4 people, 21.05%
Pain: 4 people, 21.05%
High Blood Pressure: 4 people, 21.05%
Pneumonia: 4 people, 21.05%
Haemoglobin Decreased: 3 people, 15.79%
Heart Rate Increased: 3 people, 15.79%
Ovarian Cancer (cancer of ovary): 3 people, 15.79%
Anaemia (lack of blood): 3 people, 15.79%
Reflux Gastritis (a condition in which the lining of a person's stomach becomes inflamed as a result of exposure to bile): 3 people, 15.79%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 2 people, 10.53%

* Approximation only. Some reports may have incomplete information.

Do you take Prolia and Panadol?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously