Prolia and Vancomycin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Prolia (denosumab) and Vancomycin (vancomycin). Common drug interactions include fall among females and cholecystitis among males.

The phase IV clinical study analyzes what interactions people have when they take Prolia and Vancomycin. It is created by eHealthMe based on reports of 29 people who take the same drugs from the FDA, and is updated regularly.

What is Prolia?

Prolia has active ingredients of denosumab. It is often used in osteoporosis. eHealthMe is studying from 151,388 Prolia users. Check the latest studies of Prolia.

What is Vancomycin?

Vancomycin has active ingredients of vancomycin. eHealthMe is studying from 17,165 Vancomycin users. Check the latest studies of Vancomycin.



On Jul, 04, 2026

29 people who take Prolia and Vancomycin together, and have interactions are studied.

Prolia and Vancomycin drug interactions.

What are the common drug interactions of Prolia and Vancomycin, by gender? *:

female:

  1. Fall
  2. Arthralgia (joint pain)
  3. Pain in extremity
  4. Diarrhoea
  5. Contusion (a type of hematoma of tissue in which capillaries)
  6. Back pain
  7. Constipation
  8. Localised infection (infection at the single location)
  9. Peripheral swelling
  10. Post procedural swelling

male:

  1. Cholecystitis (infection of gallbladder)
  2. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  3. Sepsis (a severe blood infection that can lead to organ failure and death)
  4. Cough
  5. Diarrhoea
  6. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  7. Anxiety
  8. Bone density decreased
  9. Emotional distress
  10. Femur fracture

What are the common drug interactions of Prolia and Vancomycin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Abdominal pain
  2. Appendicitis (inflammation of the appendix)
  3. Asthma
  4. Influenza

50-59:

  1. Abscess jaw (tooth abscess or root abscess)
  2. Flushing (the warm, red condition of human skin)
  3. Injection site erythema (redness at injection site)
  4. Weight increased

60+:

  1. Arthralgia (joint pain)
  2. Pain in extremity
  3. Kidney infection
  4. Mouth ulceration (mouth ulcers)
  5. Upper limb fracture
  6. Urinary tract infection
  7. Blood urine present
  8. Constipation
  9. Diarrhoea
  10. Localised infection (infection at the single location)

What are the existing conditions these people have? *

  1. Immunodeficiency Common Variable: 11 people, 37.93%
  2. Diarrhea: 5 people, 17.24%
  3. Urinary Tract Infection: 4 people, 13.79%
  4. Nausea And Vomiting: 4 people, 13.79%
  5. High Blood Pressure: 4 people, 13.79%
  6. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 10.34%
  7. Constipation: 3 people, 10.34%
  8. Fever: 3 people, 10.34%
  9. Gallstones (stone formation by bile component): 2 people, 6.90%
  10. Chronic Kidney Disease: 2 people, 6.90%

* Approximation only. Some reports may have incomplete information.

Do you take Prolia and Vancomycin?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Prolia and Vancomycin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Prolia:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Vancomycin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Prolia and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Vancomycin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on denosumab and vancomycin (the active ingredients of Prolia and Vancomycin, respectively), and Prolia and Vancomycin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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