Promacta and Ambien drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Promacta (eltrombopag olamine) and Ambien (zolpidem tartrate). Common drug interactions include nightmare among females and liver disorder among males.
The phase IV clinical study analyzes what interactions people have when they take Promacta and Ambien. It is created by eHealthMe based on reports of 57 people who take the same drugs from the FDA, and is updated regularly.
What is Promacta?
Promacta has active ingredients of eltrombopag olamine. It is often used in idiopathic thrombocytopenic purpura (itp). eHealthMe is studying from 17,758 Promacta users. Check the latest studies of Promacta.
What is Ambien?
Ambien has active ingredients of zolpidem tartrate. It is often used in insomnia. eHealthMe is studying from 93,519 Ambien users. Check the latest studies of Ambien.
57 people who take Promacta and Ambien together, and have interactions are studied.

What are the common drug interactions of Promacta and Ambien, by gender? *:
female:
- Nightmare (unpleasant dream)
- Pancreatitis (inflammation of pancreas)
- Pruritus (severe itching of the skin)
- Rash
- Rhinorrhoea (watery mucus discharge from the nose)
- Tremor (trembling or shaking movements in one or more parts of your body)
- Vomiting
- Weight increased
- Wheezing (a high-pitched whistling sound made while you breath)
- Adverse drug reaction
male:
- Liver disorder (liver diseases)
- Drug ineffective
- Sinusitis (inflammation of sinus)
- Abdominal distension
- Abdominal pain upper
- Abnormal dreams
- Asthenia (weakness)
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Blood calcium decreased
- Blood glucose increased
What are the common drug interactions of Promacta and Ambien, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Abnormal dreams
- Alopecia (absence of hair from areas of the body)
- Arthralgia (joint pain)
- Body temperature increased
- Dizziness
- Drug ineffective
- Dyspepsia (indigestion)
- Dyspnoea (difficult or laboured respiration)
- Fatigue (feeling of tiredness)
- Gingival bleeding (bleeding gums)
40-49:
- Pancreatitis (inflammation of pancreas)
- Platelet count decreased
- Pruritus (severe itching of the skin)
- Pyrexia (fever)
- Red blood cell count decreased
- Rhinorrhoea (watery mucus discharge from the nose)
- Tremor (trembling or shaking movements in one or more parts of your body)
- Wheezing (a high-pitched whistling sound made while you breath)
- White blood cell count decreased
- Adverse drug reaction
50-59:
- Anaemia (lack of blood)
- Disease progression
- Malignant neoplasm progression (cancer tumour came back)
- Platelet count decreased
- Red blood cell count decreased
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Septic encephalopathy (disorder or disease of the brain due to blood infection with bacteria)
- White blood cell count decreased
60+:
- Platelet count decreased
- Drug ineffective
- Epistaxis (bleed from the nose)
- Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
- Onychomycosis (fungal infection of the nail)
- Peripheral ischaemia (impaired circulation to an extremity)
- Peripheral vascular disorder
- Intervertebral disc operation
- Abdominal distension
- Abdominal pain upper
What are the existing conditions these people have? *
- Idiopathic Thrombocytopenic Purpura (bleeding disorder in which the immune system destroys platelets, which are necessary for normal blood clotting): 15 people, 26.32%
- Thrombocytopenia (decrease of platelets in blood): 9 people, 15.79%
- Hepatitis C: 4 people, 7.02%
- Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 3 people, 5.26%
* Approximation only. Some reports may have incomplete information.
Do you take Promacta and Ambien?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Promacta and Ambien:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Promacta:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Ambien:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Promacta and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Ambien and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Hsu FG, Sheu MJ, Lin CL, Hsieh YW, Lai SW, "Use of Zolpidem and Risk of Acute Pyelonephritis in Women: A Population‐Based Case‐Control Study in Taiwan", The Journal of Clinical Pharmacology, 2017 Mar .
- Lin SC, Su YC, Huang YS, Lee CC, "Zolpidem increased cancer risk in patients with sleep disorder: A 3-year follow-up study", Journal of Medical Sciences, 2016 Mar .
- Sun Y, Lin CC, Lu CJ, Hsu CY, Kao CH, "Association between zolpidem and suicide: a nationwide population-based case-control study", InMayo Clinic Proceedings, 2016 Mar .
- Liao KF, Lin CL, Lai SW, Chen WC, "Zolpidem use associated with increased risk of pyogenic liver abscess: a case-control study in Taiwan", Medicine, 2015 Jan .
- Hsu FG, Sheu MJ, Lin CL, Hsieh YW, Lai SW, "Use of Zolpidem and Risk of Acute Pyelonephritis in Women: A Population‐Based Case‐Control Study in Taiwan", The Journal of Clinical Pharmacology, 2017 Mar .
- Lin SC, Su YC, Huang YS, Lee CC, "Zolpidem increased cancer risk in patients with sleep disorder: A 3-year follow-up study", Journal of Medical Sciences, 2016 Mar .
- Sun Y, Lin CC, Lu CJ, Hsu CY, Kao CH, "Association between zolpidem and suicide: a nationwide population-based case-control study", InMayo Clinic Proceedings, 2016 Mar .
- Liao KF, Lin CL, Lai SW, Chen WC, "Zolpidem use associated with increased risk of pyogenic liver abscess: a case-control study in Taiwan", Medicine, 2015 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on eltrombopag olamine and zolpidem tartrate (the active ingredients of Promacta and Ambien, respectively), and Promacta and Ambien (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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