Promacta and Ergocalciferol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Promacta (eltrombopag olamine) and Ergocalciferol (ergocalciferol). Common drug interactions include dyspnoea among females and acute respiratory distress syndrome among males.

The phase IV clinical study analyzes what interactions people have when they take Promacta and Ergocalciferol. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Promacta?

Promacta has active ingredients of eltrombopag olamine. It is often used in idiopathic thrombocytopenic purpura (itp). eHealthMe is studying from 17,758 Promacta users. Check the latest studies of Promacta.

What is Ergocalciferol?

Ergocalciferol has active ingredients of ergocalciferol. It is often used in rickets. eHealthMe is studying from 32,652 Ergocalciferol users. Check the latest studies of Ergocalciferol.



On Jul, 18, 2026

16 people who take Promacta and Ergocalciferol together, and have interactions are studied.

Promacta and Ergocalciferol drug interactions.

What are the common drug interactions of Promacta and Ergocalciferol, by gender? *:

female:

  1. Dyspnoea (difficult or laboured respiration)
  2. Platelet count decreased
  3. Asthenia (weakness)
  4. Bacterial infection
  5. Confusional state
  6. Death
  7. Disease progression
  8. Gastric haemorrhage (bleeding stomach)
  9. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  10. Hospitalisation

male:

  1. Acute respiratory distress syndrome
  2. Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
  3. Platelet disorder
  4. Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
  5. Sepsis (a severe blood infection that can lead to organ failure and death)
  6. Tachycardia (a heart rate that exceeds the range of 100 beats/min)
  7. Tachypnoea (a condition of rapid breathing over 20 per minute)
  8. Thermal burn (burn by heat)
  9. Thrombocytopenia (decrease of platelets in blood)
  10. Disseminated intravascular coagulation (systemic activation of blood coagulation)

What are the common drug interactions of Promacta and Ergocalciferol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Hospitalisation

50-59:

  1. Febrile neutropenia (fever with reduced white blood cells)
  2. Myelodysplastic syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged)

60+:

  1. Dyspnoea (difficult or laboured respiration)
  2. Platelet count decreased
  3. Gastric haemorrhage (bleeding stomach)
  4. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  5. Haemoglobin decreased
  6. Hypersensitivity
  7. Hypotension (abnormally low blood pressure)
  8. Influenza
  9. Lobar pneumonia (a form of pneumonia that affects a large and continuous area of the lobe of a lung)
  10. Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)

What are the existing conditions these people have? *

  1. Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 2 people, 12.50%
  2. Thrombocytopenia (decrease of platelets in blood): 1 person, 6.25%
  3. Hypogonadism (reduction or absence of hormone secretion or other physiological activity of the gonads (testes or ovaries)): 1 person, 6.25%
  4. Aplastic Anemia: 1 person, 6.25%
  5. Chronic Kidney Disease: 1 person, 6.25%
  6. Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 1 person, 6.25%
  7. Diabetic Complication: 1 person, 6.25%
  8. Hepatitis B: 1 person, 6.25%
  9. Hepatitis C: 1 person, 6.25%
  10. Idiopathic Thrombocytopenic Purpura (bleeding disorder in which the immune system destroys platelets, which are necessary for normal blood clotting): 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Promacta and Ergocalciferol?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Promacta and Ergocalciferol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Promacta:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Ergocalciferol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Promacta and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ergocalciferol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on eltrombopag olamine and ergocalciferol (the active ingredients of Promacta and Ergocalciferol, respectively), and Promacta and Ergocalciferol (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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