Promacta and Isosorbide mononitrate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Promacta (eltrombopag olamine) and Isosorbide mononitrate (isosorbide mononitrate). Common drug interactions include acquired oesophageal web among females and death among males.

The phase IV clinical study analyzes what interactions people have when they take Promacta and Isosorbide mononitrate. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.

What is Promacta?

Promacta has active ingredients of eltrombopag olamine. It is often used in idiopathic thrombocytopenic purpura (itp). eHealthMe is studying from 17,758 Promacta users. Check the latest studies of Promacta.

What is Isosorbide mononitrate?

Isosorbide mononitrate has active ingredients of isosorbide mononitrate. It is often used in angina. eHealthMe is studying from 26,858 Isosorbide mononitrate users. Check the latest studies of Isosorbide mononitrate.

On Jul, 31, 2026

21 people who take Promacta and Isosorbide mononitrate together, and have interactions are studied.

Promacta and Isosorbide mononitrate drug interactions.

What are the common drug interactions of Promacta and Isosorbide Mononitrate, by gender? *:

female:

Acquired oesophageal web (structural abnormalities in the oesophagus)
Anaemia (lack of blood)
Arthralgia (joint pain)
Asthenia (weakness)
Asthma
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Back pain
Blood potassium decreased
Cardiovascular disorder (heart diseases)
Chest pain

male:

Death
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Disease progression
Dizziness
Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs)
Fatigue (feeling of tiredness)
Renal failure (kidney dysfunction)

What are the common drug interactions of Promacta and Isosorbide Mononitrate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Death

50-59:

n/a

60+:

Abdominal pain
Death
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Disease progression
Dizziness
Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs)
Fatigue (feeling of tiredness)
Renal failure (kidney dysfunction)
Thrombosis (formation of a blood clot inside a blood vessel)

What are the existing conditions these people have? *

Thrombocytopenia (decrease of platelets in blood): 4 people, 19.05%
Idiopathic Thrombocytopenic Purpura (bleeding disorder in which the immune system destroys platelets, which are necessary for normal blood clotting): 4 people, 19.05%
Pain: 2 people, 9.52%
Muscle Spasms (muscle contraction): 2 people, 9.52%
Indigestion: 2 people, 9.52%
Gastric Ulcer (stomach ulcer): 2 people, 9.52%
Cough: 2 people, 9.52%

* Approximation only. Some reports may have incomplete information.

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