Promacta and Loratadine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Promacta (eltrombopag olamine) and Loratadine (loratadine). Common drug interactions include drug ineffective among females and pneumonia among males.

The phase IV clinical study analyzes what interactions people have when they take Promacta and Loratadine. It is created by eHealthMe based on reports of 40 people who take the same drugs from the FDA, and is updated regularly.

What is Promacta?

Promacta has active ingredients of eltrombopag olamine. It is often used in idiopathic thrombocytopenic purpura (itp). eHealthMe is studying from 17,758 Promacta users. Check the latest studies of Promacta.

What is Loratadine?

Loratadine has active ingredients of loratadine. It is often used in allergies. eHealthMe is studying from 56,314 Loratadine users. Check the latest studies of Loratadine.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 27, 2026

40 people who take Promacta and Loratadine together, and have interactions are studied.

Promacta and Loratadine drug interactions.

What are the common drug interactions of Promacta and Loratadine, by gender? *:

female:

Drug ineffective
Decreased appetite
Platelet count increased
Asthenia (weakness)
Back pain
Cataract (clouding of the lens inside the eye)
Death
Fatigue (feeling of tiredness)
Hypoaesthesia (reduced sense of touch or sensation)
Memory impairment

male:

Pneumonia
Platelet count decreased
Rib fracture
Renal disorder (kidney disease)
Abdominal discomfort
Bacterial infection
Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills)
Cardiac failure congestive
Fluid retention (an abnormal accumulation of fluid in the blood)
Haemoglobin decreased

What are the common drug interactions of Promacta and Loratadine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Death

50-59:

Abdominal distension
Anaemia (lack of blood)
Death
Dyspnoea (difficult or laboured respiration)
Platelet count decreased
Pneumonia
Sepsis (a severe blood infection that can lead to organ failure and death)
Septic encephalopathy (disorder or disease of the brain due to blood infection with bacteria)
Weight increased

60+:

Pneumonia
Petechiae (a small red or purple spot caused by bleeding into the skin)
Decreased appetite
Fall
Fluid retention (an abnormal accumulation of fluid in the blood)
Furuncle (infection of the hair follicle)
Haemoglobin decreased
Hospitalisation
Insomnia (sleeplessness)
Joint swelling

What are the existing conditions these people have? *

Idiopathic Thrombocytopenic Purpura (bleeding disorder in which the immune system destroys platelets, which are necessary for normal blood clotting): 6 people, 15.00%
Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 4 people, 10.00%
Thrombocytopenia (decrease of platelets in blood): 3 people, 7.50%
Multiple Myeloma (cancer of the plasma cells): 2 people, 5.00%
Lung Neoplasm Malignant (cancer tumour of lung): 2 people, 5.00%
Breast Cancer Female: 2 people, 5.00%

* Approximation only. Some reports may have incomplete information.

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