Promacta and Promethazine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Promacta (eltrombopag olamine) and Promethazine (promethazine hydrochloride). Common drug interactions include death among females and platelet count decreased among males.

The phase IV clinical study analyzes what interactions people have when they take Promacta and Promethazine. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.

What is Promacta?

Promacta has active ingredients of eltrombopag olamine. It is often used in idiopathic thrombocytopenic purpura (itp). eHealthMe is studying from 17,758 Promacta users. Check the latest studies of Promacta.

What is Promethazine?

Promethazine has active ingredients of promethazine hydrochloride. It is often used in nausea. eHealthMe is studying from 32,300 Promethazine users. Check the latest studies of Promethazine.

On Jul, 12, 2026

26 people who take Promacta and Promethazine together, and have interactions are studied.

Promacta and Promethazine drug interactions.

What are the common drug interactions of Promacta and Promethazine, by gender? *:

female:

Death
Diarrhoea
Epigastric discomfort
Nasopharyngitis (inflammation of the nasopharynx)
Anaemia (lack of blood)
Thrombocytopenia (decrease of platelets in blood)
Headache (pain in head)
Subdural haematoma (blood collects between the skull and the surface of the brain)
Asthenia (weakness)
Bone disorder

male:

Platelet count decreased
Abdominal pain
Abasia (inability to walk)
Anger
Aphagia (inability or refusal to swallow)
Asthenia (weakness)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Bone pain
Cellulitis (infection under the skin)
Contusion (a type of hematoma of tissue in which capillaries)

What are the common drug interactions of Promacta and Promethazine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Alanine aminotransferase increased
Aspartate aminotransferase increased
Blood bilirubin increased
Drug-induced liver injury (diseases of the liver that are caused by physician-prescribed medications)
Gamma-glutamyltransferase increased

30-39:

n/a

40-49:

Subdural haematoma (blood collects between the skull and the surface of the brain)
Asthenia (weakness)
Fall
Rib fracture
Thrombocytopenia (decrease of platelets in blood)
Urinary tract infection
Head injury
Hepatic encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure)
Loss of consciousness

50-59:

Abdominal pain
Dizziness
Fatigue (feeling of tiredness)
Gastric disorder (disease of stomach)
Hepatic pain (pain in liver)
Loss of consciousness
Platelet count decreased
Bone density decreased
Feeding disorder (when children refuse to eat certain food groups)
Activities of daily living impaired

60+:

Anaemia (lack of blood)
Death
Anaemia macrocytic (a macrocytic class of anaemia)
Chronic myelomonocytic leukaemia (cancers of the blood-forming cells of the bone marrow)
Fatigue (feeling of tiredness)
Haemorrhage (bleeding)
Increased tendency to bruise (increased tendency to injure the underlying soft tissue or bone)
Leukaemia (blood or bone marrow cancer)
Leukocytosis (increased white blood cells)
Pallor

What are the existing conditions these people have? *

Hepatitis C: 4 people, 15.38%
Back Pain: 3 people, 11.54%
Lung Cancer - Non-Small Cell (lung cancer): 2 people, 7.69%
Joint Pain: 2 people, 7.69%
Insomnia (sleeplessness): 2 people, 7.69%
Hypovitaminosis (any of several diseases caused by deficiency of one or more vitamins): 2 people, 7.69%
Aplastic Anemia: 2 people, 7.69%
Adverse Event: 2 people, 7.69%

* Approximation only. Some reports may have incomplete information.

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