Promethazine and Bifidobacterium drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Promethazine (promethazine hydrochloride) and Bifidobacterium (bifidobacteria). Common drug interactions include neutrophil count decreased among females and cardiac failure among males.

The phase IV clinical study analyzes what interactions people have when they take Promethazine and Bifidobacterium. It is created by eHealthMe based on reports of 66 people who take the same drugs from the FDA, and is updated regularly.

What is Promethazine?

Promethazine has active ingredients of promethazine hydrochloride. It is often used in nausea. eHealthMe is studying from 32,300 Promethazine users. Check the latest studies of Promethazine.

What is Bifidobacterium?

Bifidobacterium has active ingredients of bifidobacteria. eHealthMe is studying from 5,013 Bifidobacterium users. Check the latest studies of Bifidobacterium.

On Jul, 23, 2026

66 people who take Promethazine and Bifidobacterium together, and have interactions are studied.

Promethazine and Bifidobacterium drug interactions.

What are the common drug interactions of Promethazine and Bifidobacterium, by gender? *:

female:

Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
Oral candidiasis (fungal infection of mouth)
Proctitis (inflammation of the rectum and anus)
Spinal disorder (disease of spine a back bone)
Thrombocytopenia (decrease of platelets in blood)
Vaginal discharge
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Arterial occlusive disease (slow process through which arteries throughout the body become progressively narrowed and eventually completely blocked)
Arthralgia (joint pain)
Malaise (a feeling of general discomfort or uneasiness)

male:

Cardiac failure
Myelosuppression (a decrease in the production of blood cells)
Hyposmia (impairment of the sense of smell)
Impaired gastric emptying
Increased appetite
Memory impairment
Muscle spasms (muscle contraction)
Nephrolithiasis (calculi in the kidneys)
Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)
Palpitations (feelings or sensations that your heart is pounding or racing)

What are the common drug interactions of Promethazine and Bifidobacterium, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Anxiety
Back pain
Cat scratch disease (bacterial infection by cat scratch)
Coma (state of unconsciousness lasting more than six hours)
Constipation
Cyclic vomiting syndrome (prolonged episodes of severe nausea, vomiting)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Drug ineffective
Dyskinesia (abnormality or impairment of voluntary movement)
Emotional distress

30-39:

Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
Disease recurrence
Gastric bypass
Impaired gastric emptying
Somnolence (a state of near-sleep, a strong desire for sleep)
Stress
Weight decreased

40-49:

Constipation
Headache (pain in head)
Infusion site bruising
Infusion site infection
Pyrexia (fever)
Skin injury
Abdominal pain upper
Alopecia (absence of hair from areas of the body)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)

50-59:

Chronic kidney disease
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Dizziness
Dyspnoea (difficult or laboured respiration)
Ear disorder
Emotional distress
Eye disorder
Faeces discoloured
Fanconi syndrome acquired (self developed genetic disease of kidney damage due to defective transport system)
Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)

60+:

Anaemia (lack of blood)
Leukopenia (less number of white blood cells in blood)
Cardiac failure
Chronic sinusitis (long lasting inflammation of the paranasal sinuses)
Colitis (inflammation of colon)
Colitis ulcerative (inflammation of colon with ulcer)
Drug ineffective
Erythema (redness of the skin)
Female genital tract fistula (passage in genital tract of female)
Frequent bowel movements

What are the existing conditions these people have? *

Immunodeficiency Common Variable: 17 people, 25.76%
Asthma: 11 people, 16.67%
Pain: 11 people, 16.67%
Fever: 9 people, 13.64%
Stress And Anxiety: 8 people, 12.12%
Blood Glucose Decreased: 8 people, 12.12%
High Blood Pressure: 8 people, 12.12%
Short-Bowel Syndrome (a condition in which the body cannot absorb enough fluids and nutrients because part of the small intestine is missing): 7 people, 10.61%
Blood Iron Decreased: 7 people, 10.61%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 10.61%

* Approximation only. Some reports may have incomplete information.

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