Promethazine and Efudex drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Promethazine (promethazine hydrochloride) and Efudex (fluorouracil). Common drug interactions include asthma among females and chronic kidney disease among males.
The phase IV clinical study analyzes what interactions people have when they take Promethazine and Efudex. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.
What is Promethazine?
Promethazine has active ingredients of promethazine hydrochloride. It is often used in nausea. eHealthMe is studying from 32,300 Promethazine users. Check the latest studies of Promethazine.
What is Efudex?
Efudex has active ingredients of fluorouracil. It is often used in actinic keratosis. eHealthMe is studying from 1,391 Efudex users. Check the latest studies of Efudex.
16 people who take Promethazine and Efudex together, and have interactions are studied.
What are the common drug interactions of Promethazine and Efudex, by gender? *:
female:
- Asthma
- Autoimmune disorder (a condition in which the immune system attacks the body's normal substances and tissue)
- Blood pressure increased
- Depression
- Drug hypersensitivity
- Hair disorder
- Hypoglycaemia (deficiency of glucose in the bloodstream)
- Neuropathy peripheral (surface nerve damage)
- Pulmonary mass
- Raynaud's phenomenon (discoloration of the fingers, toes, and occasionally other areas)
male:
- Chronic kidney disease
- Renal failure (kidney dysfunction)
What are the common drug interactions of Promethazine and Efudex, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
50-59:
- Hair colour changes
- Surgery
- Renal failure (kidney dysfunction)
- Alopecia (absence of hair from areas of the body)
- Depression
- Hair disorder
- Alopecia areata (patchy baldness that typically begins with rapid hair loss)
- Chronic kidney disease
- Diarrhoea
- Gastroenteritis (inflammation of stomach and intestine)
60+:
n/a
What are the existing conditions these people have? *
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 11 people, 68.75%
- Pain: 5 people, 31.25%
- Breast Cancer Female: 3 people, 18.75%
- Urinary Retention (the inability to completely or partially empty the bladder): 1 person, 6.25%
- Stress And Anxiety: 1 person, 6.25%
- Parkinson's Disease: 1 person, 6.25%
- Motion Sickness (travel sickness): 1 person, 6.25%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 6.25%
- Diarrhea: 1 person, 6.25%
- Constipation: 1 person, 6.25%
* Approximation only. Some reports may have incomplete information.
Do you take Promethazine and Efudex?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Promethazine (32,300 reports)
- Efudex (1,391 reports)
Browse all drug interactions of Promethazine and Efudex:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Promethazine:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Efudex:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Promethazine and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Efudex and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Teimoory M, Arefi M, Behnoush B, Bastani B, "Promethazine and Treatment Refractory Agitation in Clonidine Toxicity", International Journal of Medical Toxicology and Forensic Medicine, 2013 Mar .
- Teimoory M, Arefi M, Behnoush B, Bastani B, "Promethazine and Treatment Refractory Agitation in Clonidine Toxicity", International Journal of Medical Toxicology and Forensic Medicine, 2013 Mar .
How the study uses the data?
The study uses data from the FDA. It is based on promethazine hydrochloride and fluorouracil (the active ingredients of Promethazine and Efudex, respectively), and Promethazine and Efudex (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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