Promethazine and Tarceva drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Promethazine (promethazine hydrochloride) and Tarceva (erlotinib hydrochloride). Common drug interactions include cerebrovascular accident among females and death among males.

The phase IV clinical study analyzes what interactions people have when they take Promethazine and Tarceva. It is created by eHealthMe based on reports of 69 people who take the same drugs from the FDA, and is updated regularly.

What is Promethazine?

Promethazine has active ingredients of promethazine hydrochloride. It is often used in nausea. eHealthMe is studying from 32,300 Promethazine users. Check the latest studies of Promethazine.

What is Tarceva?

Tarceva has active ingredients of erlotinib hydrochloride. It is often used in lung cancer. eHealthMe is studying from 31,036 Tarceva users. Check the latest studies of Tarceva.

On Jul, 15, 2026

69 people who take Promethazine and Tarceva together, and have interactions are studied.

Promethazine and Tarceva drug interactions.

What are the common drug interactions of Promethazine and Tarceva, by gender? *:

female:

Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Asthenia (weakness)
Weight decreased
Rhinorrhoea (watery mucus discharge from the nose)
Skin fissures (a crack in the skin)
Haematochezia (passage of stools containing blood)
Dry skin
Onychomadesis (a periodic idiopathic shedding of the nails)
Skin exfoliation (removal of the oldest dead skin cells)
Skin haemorrhage (bleeding into skin)

male:

Death
Rash
Hypoxia (low oxygen in tissues)
Weight decreased
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Headache (pain in head)
Asthenia (weakness)
Confusional state
Cough
Feeding disorder (when children refuse to eat certain food groups)

What are the common drug interactions of Promethazine and Tarceva, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Death

50-59:

Rash
Drug ineffective
Scab (a hard coating on the skin formed during the wound healing)
Death
Pain
Pruritus (severe itching of the skin)

60+:

Diarrhoea
Rash
Haematochezia (passage of stools containing blood)
Oral pain
Blood pressure decreased
Dermatitis acneiform (dermatoses including acne vulgaris, rosacea, folliculitis, and perioral dermatitis)
Dry skin
Epistaxis (bleed from the nose)
Erythema (redness of the skin)
Eye discharge

What are the existing conditions these people have? *

Lung Neoplasm Malignant (cancer tumour of lung): 47 people, 68.12%
Pain: 7 people, 10.14%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 5 people, 7.25%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 5 people, 7.25%
Type 2 Diabetes: 4 people, 5.80%
High Blood Pressure: 4 people, 5.80%

* Approximation only. Some reports may have incomplete information.

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