Promethegan and Nitroglycerin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Promethegan (promethazine hydrochloride) and Nitroglycerin (nitroglycerin). Common drug interactions include renal failure among females.

The phase IV clinical study analyzes what interactions people have when they take Promethegan and Nitroglycerin. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Promethegan?

Promethegan has active ingredients of promethazine hydrochloride. It is often used in nausea. eHealthMe is studying from 428 Promethegan users. Check the latest studies of Promethegan.

What is Nitroglycerin?

Nitroglycerin has active ingredients of nitroglycerin. It is often used in chest pain. eHealthMe is studying from 52,884 Nitroglycerin users. Check the latest studies of Nitroglycerin.

On Aug, 07, 2026

18 people who take Promethegan and Nitroglycerin together, and have interactions are studied.

Promethegan and Nitroglycerin drug interactions.

What are the common drug interactions of Promethegan and Nitroglycerin, by gender? *:

female:

Renal failure (kidney dysfunction)
Headache (pain in head)
Hyperkalaemia (damage to or disease of the kidney)
Hypertension (high blood pressure)
Ischaemic cardiomyopathy (weakness in the muscle of the heart due to inadequate oxygen delivery to the myocardium with coronary artery disease)
Oedema peripheral (superficial swelling)
Palpitations (feelings or sensations that your heart is pounding or racing)
Pyrexia (fever)
Ventricular tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart)
Vitreous detachment (a condition of the eye in which the vitreous humour separates from the retina)

male:

n/a

What are the common drug interactions of Promethegan and Nitroglycerin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Chronic kidney disease
Angina unstable (chest pain due to ischemia of the heart muscle- unstable)
Asthenia (weakness)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Bundle branch block left (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the left ventricle)
Cardiac disorder
Cardiac failure chronic
Cardiac valve disease (heart valve disease)
Cardiomyopathy (weakening of the heart muscle)
Cellulitis (infection under the skin)

50-59:

Intestinal obstruction
Ovarian adhesion (bands of scar-like tissue that form between ovary and nearby organ)
Pain
Palpitations (feelings or sensations that your heart is pounding or racing)
Pelvic adhesions
Pelvic pain
Salpingitis (an infection and inflammation in the fallopian tubes)
Tricuspid valve incompetence (inefficient heart valve)
Abdominal pain upper
Anxiety

60+:

Renal failure (kidney dysfunction)
Cough
Asthenia (weakness)
Dehydration (dryness resulting from the removal of water)
Diabetic retinopathy (damage to the retina caused by complications of diabetes)
Dizziness
Dyspnoea (difficult or laboured respiration)
Headache (pain in head)
Heart rate decreased
Hypercholesterolaemia (high levels of cholesterol in the blood)

What are the existing conditions these people have? *

Arrhythmias (irregular heartbeat): 7 people, 38.89%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 33.33%
Herpes Zoster: 5 people, 27.78%
Pain: 5 people, 27.78%
Diabetes: 5 people, 27.78%
The Flu (the flu is caused by an influenza virus): 5 people, 27.78%
Gastric Ulcer (stomach ulcer): 5 people, 27.78%
Headache (pain in head): 5 people, 27.78%
High Blood Cholesterol: 5 people, 27.78%
High Blood Pressure: 5 people, 27.78%

* Approximation only. Some reports may have incomplete information.

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