Promethegan and Restasis drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Promethegan (promethazine hydrochloride) and Restasis (cyclosporine). Common drug interactions include chronic kidney disease among females.

The phase IV clinical study analyzes what interactions people have when they take Promethegan and Restasis. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Promethegan?

Promethegan has active ingredients of promethazine hydrochloride. It is often used in nausea. eHealthMe is studying from 428 Promethegan users. Check the latest studies of Promethegan.

What is Restasis?

Restasis has active ingredients of cyclosporine. It is often used in dry eyes. eHealthMe is studying from 35,199 Restasis users. Check the latest studies of Restasis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 22, 2026

11 people who take Promethegan and Restasis together, and have interactions are studied.

Promethegan and Restasis drug interactions.

What are the common drug interactions of Promethegan and Restasis, by gender? *:

female:

Chronic kidney disease
Renal failure (kidney dysfunction)
Nephrogenic anaemia (anaemia due to kidney disease)
Renal tubular necrosis (death of kidney tubules)
Decreased appetite
Dehydration (dryness resulting from the removal of water)
Febrile neutropenia (fever with reduced white blood cells)
Foot deformity (functional disability of foot)

male:

n/a

What are the common drug interactions of Promethegan and Restasis, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

Chronic kidney disease
Renal failure (kidney dysfunction)
Nephrogenic anaemia (anaemia due to kidney disease)
Renal tubular necrosis (death of kidney tubules)
Decreased appetite
Dehydration (dryness resulting from the removal of water)
Febrile neutropenia (fever with reduced white blood cells)
Foot deformity (functional disability of foot)

What are the existing conditions these people have? *

Anaemia (lack of blood): 8 people, 72.73%
Diarrhea: 8 people, 72.73%
Stress And Anxiety: 8 people, 72.73%
High Blood Pressure: 8 people, 72.73%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 8 people, 72.73%
Depression: 8 people, 72.73%
High Blood Cholesterol: 6 people, 54.55%
Hiv Infection: 6 people, 54.55%
Tooth Abscess (pus formation in tooth): 6 people, 54.55%
Insomnia (sleeplessness): 6 people, 54.55%

* Approximation only. Some reports may have incomplete information.

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