Promethegan and Temaz drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Promethegan (promethazine hydrochloride) and Temaz (temazepam). Common drug interactions include dizziness among females and abdominal pain among males.

The phase IV clinical study analyzes what interactions people have when they take Promethegan and Temaz. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.

What is Promethegan?

Promethegan has active ingredients of promethazine hydrochloride. It is often used in nausea. eHealthMe is studying from 428 Promethegan users. Check the latest studies of Promethegan.

What is Temaz?

Temaz has active ingredients of temazepam. It is often used in insomnia. eHealthMe is studying from 42,293 Temaz users. Check the latest studies of Temaz.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 23, 2026

23 people who take Promethegan and Temaz together, and have interactions are studied.

Promethegan and Temaz drug interactions.

What are the common drug interactions of Promethegan and Temaz, by gender? *:

female:

Dizziness
Hyperkalaemia (damage to or disease of the kidney)
Hypertension (high blood pressure)
Ischaemic cardiomyopathy (weakness in the muscle of the heart due to inadequate oxygen delivery to the myocardium with coronary artery disease)
Oedema peripheral (superficial swelling)
Pyrexia (fever)
Ventricular tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart)
Vitreous detachment (a condition of the eye in which the vitreous humour separates from the retina)
Mitral valve incompetence (inefficient heart valve)
Cardiac valve disease (heart valve disease)

male:

Abdominal pain
Blood in stool

What are the common drug interactions of Promethegan and Temaz, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Cardiac arrest
Dyspnoea (difficult or laboured respiration)
Folliculitis (infection of hair root)
Lung disorder (lung disease)
Chest discomfort
Chest pain
Chronic kidney disease
Renal failure (kidney dysfunction)

40-49:

Angina pectoris (chest pain due to ischemia of the heart muscle)
Angina unstable (chest pain due to ischemia of the heart muscle- unstable)
Asthenia (weakness)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Bundle branch block left (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the left ventricle)
Cardiac disorder
Cardiac failure chronic
Cardiac valve disease (heart valve disease)
Cardiomyopathy (weakening of the heart muscle)
Cellulitis (infection under the skin)

50-59:

Fibromyalgia (a long-term condition which causes pain all over the body)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Headache (pain in head)
Hypertriglyceridaemia (excess of triglycerides in the blood)
Injury
Intestinal obstruction
Obesity (having too much body fat)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Ovarian adhesion (bands of scar-like tissue that form between ovary and nearby organ)
Ovarian cyst (fluid filled sac of the ovary)

60+:

Renal failure (kidney dysfunction)
Vitreous haemorrhage (intraocular (inside the eye) bleeding)
Dehydration (dryness resulting from the removal of water)
Diabetic retinopathy (damage to the retina caused by complications of diabetes)
Dizziness
Dyspnoea (difficult or laboured respiration)
Headache (pain in head)
Heart rate decreased
Hypercholesterolaemia (high levels of cholesterol in the blood)
Hypertension (high blood pressure)

What are the existing conditions these people have? *

Arrhythmias (irregular heartbeat): 7 people, 30.43%
Stress And Anxiety: 3 people, 13.04%
High Blood Pressure: 3 people, 13.04%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 13.04%
Cystic Fibrosis (disease of the secretary glands): 3 people, 13.04%
High Blood Cholesterol: 2 people, 8.70%
Depression: 2 people, 8.70%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 2 people, 8.70%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 2 people, 8.70%

* Approximation only. Some reports may have incomplete information.

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