Propofol and Itraconazole drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Propofol (propofol) and Itraconazole (itraconazole). Common drug interactions include epstein-barr virus associated lymphoproliferative disorder among females and gastrointestinal disorder among males.

The phase IV clinical study analyzes what interactions people have when they take Propofol and Itraconazole. It is created by eHealthMe based on reports of 48 people who take the same drugs from the FDA, and is updated regularly.

What is Propofol?

Propofol has active ingredients of propofol. It is often used in colonoscopy abnormal. eHealthMe is studying from 38,224 Propofol users. Check the latest studies of Propofol.

What is Itraconazole?

Itraconazole has active ingredients of itraconazole. It is often used in fungal infection. eHealthMe is studying from 12,372 Itraconazole users. Check the latest studies of Itraconazole.

On Jul, 21, 2026

48 people who take Propofol and Itraconazole together, and have interactions are studied.

Propofol and Itraconazole drug interactions.

What are the common drug interactions of Propofol and Itraconazole, by gender? *:

female:

Epstein-barr virus associated lymphoproliferative disorder (lymphocytes are produced in excessive quantities associated with epstein-barr virus)
Hepatitis (inflammation of the liver)
Hyperpyrexia (extremely high fever)
Hypertransaminasaemia
Urinary tract infection
Cardiac failure
Herpes zoster
Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
Alanine aminotransferase increased
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)

male:

Gastrointestinal disorder (functional problems of gastrointestinal tract)
Cough
Pulmonary function test decreased
Splenomegaly (enlargement of spleen)
Pulmonary embolism (blockage of the main artery of the lung)
General physical health deterioration (weak health status)
International normalised ratio increased
Pyrexia (fever)
Pneumonia
Pneumonitis (inflammation of the walls of the alveoli in the lungs)

What are the common drug interactions of Propofol and Itraconazole, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Cough
Cystic fibrosis related diabetes
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue)
Hepatic mass
Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus)
Obstructive airways disorder (a progressive disease that makes it hard to breathe)
Pancreatic atrophy
Platelet count decreased
Portal hypertension (increase in the blood pressure within a system of veins called the portal venous system)

20-29:

Alanine aminotransferase increased
Aspartate aminotransferase increased
Blood alkaline phosphatase nos increased
Dyspnoea (difficult or laboured respiration)
Hypercapnia (too much smoke)
International normalised ratio increased
Tachypnoea (a condition of rapid breathing over 20 per minute)

30-39:

Hepatitis acute
Blood creatine phosphokinase increased
Hepatitis (inflammation of the liver)
Hyperpyrexia (extremely high fever)
Hypertransaminasaemia
Alanine aminotransferase increased
Compartment syndrome (painful condition that occurs when pressure within the muscles builds to dangerous levels)
Hypertriglyceridaemia (excess of triglycerides in the blood)
Renal failure acute (rapid kidney dysfunction)
Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)

40-49:

Arrhythmia (irregular heartbeat)
Encephalopathy (functioning of the brain is affected by some agent or condition)
Pneumonitis (inflammation of the walls of the alveoli in the lungs)
Sepsis (a severe blood infection that can lead to organ failure and death)

50-59:

Sepsis (a severe blood infection that can lead to organ failure and death)
Urinary tract infection
Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Drug hypersensitivity
Drug toxicity
Epidermal necrolysis (skin condition that is usually caused by a reaction to drugs)
Gastroenteritis (inflammation of stomach and intestine)

60+:

Pneumonia
Pulmonary embolism (blockage of the main artery of the lung)
Blood bilirubin increased
Blood cholinesterase increased
Catheter site haemorrhage (bleeding at catheter site)
Chills (felling of cold)
Disseminated intravascular coagulation (systemic activation of blood coagulation)
Drug hypersensitivity
Electrolyte imbalance
Embolism (obstruction of an artery, typically by a clot of blood or an air bubble)

What are the existing conditions these people have? *

Sedation: 12 people, 25.00%
Fever: 10 people, 20.83%
High Blood Pressure: 9 people, 18.75%
Infection: 7 people, 14.58%
Aplastic Anemia: 6 people, 12.50%
Agitation (state of anxiety or nervous excitement): 6 people, 12.50%
Diabetes: 5 people, 10.42%
Pneumonia: 5 people, 10.42%
Sepsis (a severe blood infection that can lead to organ failure and death): 5 people, 10.42%
Insomnia (sleeplessness): 5 people, 10.42%

* Approximation only. Some reports may have incomplete information.

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