Propranolol hydrochloride and Modafinil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Propranolol hydrochloride (propranolol hydrochloride) and Modafinil (modafinil). Common drug interactions include multiple sclerosis relapse among females and back pain among males.

The phase IV clinical study analyzes what interactions people have when they take Propranolol hydrochloride and Modafinil. It is created by eHealthMe based on reports of 50 people who take the same drugs from the FDA, and is updated regularly.

What is Propranolol hydrochloride?

Propranolol hydrochloride has active ingredients of propranolol hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 12,026 Propranolol hydrochloride users. Check the latest studies of Propranolol hydrochloride.

What is Modafinil?

Modafinil has active ingredients of modafinil. It is often used in narcolepsy. eHealthMe is studying from 20,805 Modafinil users. Check the latest studies of Modafinil.

On Jul, 04, 2026

50 people who take Propranolol hydrochloride and Modafinil together, and have interactions are studied.

Propranolol hydrochloride and Modafinil drug interactions.

What are the common drug interactions of Propranolol Hydrochloride and Modafinil, by gender? *:

female:

Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Nervousness
Osteopenia (a condition where bone mineral density is lower than normal)
Paranoia (psychotic disorder characterized by delusions of persecution with or without grandeur)
Peritoneal disorder
Pharyngitis streptococcal (inflammation of the pharynx caused by infection from. streptococcus)
Polytraumatism (multiple trauma)
Postoperative wound complication
Pruritus (severe itching of the skin)
Skin infection

male:

Back pain
Central nervous system lesion (an abnormality in tissue of brain or spinal cord)
Loss of consciousness
Pneumonia
Blood cholesterol increased
Cough
Facial paresis (weakness in facial muscle movement)
Fibromyalgia (a long-term condition which causes pain all over the body)
Irritable bowel syndrome
Multiple drug overdose intentional

What are the common drug interactions of Propranolol Hydrochloride and Modafinil, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Balance disorder
Diplopia (double vision)
Fibromyalgia (a long-term condition which causes pain all over the body)
Headache (pain in head)
Inappropriate affect
Nervousness
Paranoia (psychotic disorder characterized by delusions of persecution with or without grandeur)
Snoring
Tooth disorder (tooth disease)
Weight decreased

40-49:

Alopecia (absence of hair from areas of the body)
Anaphylactic reaction (serious allergic reaction)
Hypoaesthesia (reduced sense of touch or sensation)
Influenza like illness
Limb discomfort (discomfort in leg)

50-59:

Obsessive-compulsive disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;)
Oedema peripheral (superficial swelling)
Osteonecrosis (death of bone)
Panic attack
Pericardial disease
Peritoneal disorder
Pain
Abdominal distension
Abdominal pain
Agitation (state of anxiety or nervous excitement)

60+:

Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Completed suicide (act of taking one's own life)
Cough
Multiple drug overdose intentional
Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
Fall
Hernia (hernia happens when part of an internal organ or tissue bulges through a weak area of muscle)
Intervertebral disc protrusion (spinal disc protrusion)
Pain
Pharyngitis streptococcal (inflammation of the pharynx caused by infection from. streptococcus)

What are the existing conditions these people have? *

Cataplexy (loss of muscle tone accompanied by full conscious awareness): 18 people, 36.00%
Drowsiness: 11 people, 22.00%
Bipolar Disorder (mood disorder): 8 people, 16.00%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 7 people, 14.00%
Depression: 5 people, 10.00%
Nausea (feeling of having an urge to vomit): 4 people, 8.00%
Panic Disorder: 3 people, 6.00%

* Approximation only. Some reports may have incomplete information.

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