Propulsid and Cordarone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Propulsid (cisapride monohydrate) and Cordarone (amiodarone hydrochloride). Common drug interactions include supraventricular tachycardia among females and cardiac failure congestive among males.

The phase IV clinical study analyzes what interactions people have when they take Propulsid and Cordarone. It is created by eHealthMe based on reports of 44 people who take the same drugs from the FDA, and is updated regularly.

What is Propulsid?

Propulsid has active ingredients of cisapride monohydrate. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 8,130 Propulsid users. Check the latest studies of Propulsid.

What is Cordarone?

Cordarone has active ingredients of amiodarone hydrochloride. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 22,776 Cordarone users. Check the latest studies of Cordarone.

On Jul, 06, 2026

44 people who take Propulsid and Cordarone together, and have interactions are studied.

Propulsid and Cordarone drug interactions.

What are the common drug interactions of Propulsid and Cordarone, by gender? *:

female:

Supraventricular tachycardia (rapid heart rhythm originating at or above the atrioventricular node)
Sweating increased (excess sweating)
Urinary incontinence (inability to control the flow of urine and involuntary urination)
Ventricular fibrillation (abnormally irregular heart rhythm)
Viral infection
Weakness
Weight decreased
Alveolitis allergic (inflammation of the alveoli within the lung caused by hypersensitivity to inhaled organic dusts)
Anal fissure
Atrial tachycardia (rhythm disturbance that arises in the atria)

male:

Cardiac failure congestive
Torsade de pointes (a abnormal heart rate with abnormal beating pattern)
Respiratory tract infection
Ventricular fibrillation (abnormally irregular heart rhythm)
Weakness
Agitation (state of anxiety or nervous excitement)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Appetite decreased (decreased appetite occurs when you have a reduced desire to eat)
Arthralgia (joint pain)
Asthenia (weakness)

What are the common drug interactions of Propulsid and Cordarone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Fall
Fatigue (feeling of tiredness)
Frequent bowel movements
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Haemorrhoids (a swollen vein or group of veins in the region of the anus)
Hypoglycaemia (deficiency of glucose in the bloodstream)
International normalised ratio increased
Oedema lower limb (fluid collection in tissue of lower leg)
Palpitations (feelings or sensations that your heart is pounding or racing)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)

60+:

Ventricular fibrillation (abnormally irregular heart rhythm)
Cardiac disorder
Vomiting
Atrioventricular block (heart block)
Atrioventricular block complete (heart block complete)
Bronchitis acute (acute inflammation of the mucous membrane in the bronchial tubes)
Bundle branch block right (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the right ventricle)
Cardiac arrest
Choreoathetosis (involuntary movement randomly from one part to another body part)
Dementia (madness)

What are the existing conditions these people have? *

Cardiomyopathy (weakening of the heart muscle): 5 people, 11.36%

* Approximation only. Some reports may have incomplete information.

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