Propulsid and Macrodantin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Propulsid (cisapride monohydrate) and Macrodantin (nitrofurantoin, macrocrystalline). Common drug interactions include renal failure acute among females.

The phase IV clinical study analyzes what interactions people have when they take Propulsid and Macrodantin. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Propulsid?

Propulsid has active ingredients of cisapride monohydrate. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 8,130 Propulsid users. Check the latest studies of Propulsid.

What is Macrodantin?

Macrodantin has active ingredients of nitrofurantoin, macrocrystalline. It is often used in urinary tract infection. eHealthMe is studying from 3,755 Macrodantin users. Check the latest studies of Macrodantin.

On Jul, 08, 2026

15 people who take Propulsid and Macrodantin together, and have interactions are studied.

Propulsid and Macrodantin drug interactions.

What are the common drug interactions of Propulsid and Macrodantin, by gender? *:

female:

Renal failure acute (rapid kidney dysfunction)
Abscess (pus)
Back pain
Cardiac failure congestive
Cataract (clouding of the lens inside the eye)
Constipation
Dehydration (dryness resulting from the removal of water)
Depression
Diabetes mellitus inadequate control
Drug hypersensitivity

male:

n/a

What are the common drug interactions of Propulsid and Macrodantin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Asthenia (weakness)
Headache (pain in head)
Influenza like illness
Thinking abnormal

40-49:

Contrast media reaction (reaction associated with the use of intravenous contrast material during radiology)
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Coronary artery thrombosis (clot formation in coronary artery)
Cough
Cystitis glandularis (forming a timorous lesion with blueberry spots in the urinary bladder)
Deafness
Decreased appetite
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Dehydration (dryness resulting from the removal of water)
Depression

50-59:

Atrial flutter (an abnormal heart rhythm that occurs in the atria of the heart)
Back pain
Blindness unilateral
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Blood potassium decreased
Bundle branch block left (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the left ventricle)
Cardiac failure congestive
Cataract (clouding of the lens inside the eye)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Congestive cardiomyopathy (weakening of heart muscle)

60+:

Abdominal pain
Constipation
Death
Drug hypersensitivity
Electrocardiogram qt corrected interval prolonged
Lethargy (tiredness)

What are the existing conditions these people have? *

Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 20.00%
Stress And Anxiety: 1 person, 6.67%
Sleep Disorder: 1 person, 6.67%
Pulmonary Congestion (congestion in the lungs): 1 person, 6.67%
Pain: 1 person, 6.67%
Osteopenia (a condition where bone mineral density is lower than normal): 1 person, 6.67%
Impaired Gastric Emptying: 1 person, 6.67%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 6.67%
Hyperlipidaemia (presence of excess lipids in the blood): 1 person, 6.67%
High Blood Pressure: 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

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