Propylthiouracil and Iodine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Propylthiouracil (propylthiouracil) and Iodine (iodine). Common drug interactions include drug ineffective among females and drug ineffective among males.

The phase IV clinical study analyzes what interactions people have when they take Propylthiouracil and Iodine. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.

What is Propylthiouracil?

Propylthiouracil has active ingredients of propylthiouracil. It is often used in hyperthyroidism. eHealthMe is studying from 2,545 Propylthiouracil users. Check the latest studies of Propylthiouracil.

What is Iodine?

Iodine has active ingredients of iodine. It is often used in hypothyroidism. eHealthMe is studying from 3,807 Iodine users. Check the latest studies of Iodine.

On Aug, 03, 2026

20 people who take Propylthiouracil and Iodine together, and have interactions are studied.

Propylthiouracil and Iodine drug interactions.

What are the common drug interactions of Propylthiouracil and Iodine, by gender? *:

female:

Drug ineffective
Maternal exposure during pregnancy (use of substance during pregnancy)
Acute hepatic failure
Hepatic encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure)
Normal newborn
Episcleritis (acute inflammatory disorder of the episclera of eye)
Glomerulonephritis rapidly progressive (a syndrome of the kidney that is characterized by a rapid loss of renal function)
Pulmonary haemorrhage (acute bleeding from the lung)
Vasculitis (inflammation of a blood vessel or blood vessels)
Assisted delivery

male:

Drug ineffective
Cardiogenic shock (inadequate circulation of blood)
Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)
Hepatic failure (liver failure)
Mental impairment (a condition affecting the body, perhaps through sight or hearing loss, a mobility difficulty or a health condition)
Myopericarditis (disease caused by inflammation of the myocardium (muscle of the heart wall) and/or the pericardium)
Renal failure (kidney dysfunction)
Talipes
Acute hepatic failure
Acute myocardial infarction (acute heart attack)

What are the common drug interactions of Propylthiouracil and Iodine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Drug ineffective
Drug resistance (reduction in effectiveness of a drug)
Nephrogenic diabetes insipidus (a disorder in which a defect in the small tubes (tubules) in the kidneys causes a person to pass a large amount of urine)
Palpitations (feelings or sensations that your heart is pounding or racing)
Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node)

20-29:

Blood pressure decreased
Cardiac arrest
Drug ineffective
Foetal death (death of foetus)
Lupus-like syndrome (a disease symptom matches with lupus an immune disease)
Pulseless electrical activity

30-39:

Acute hepatic failure
Hepatic encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure)
Maternal exposure during pregnancy (use of substance during pregnancy)
Normal newborn
Episcleritis (acute inflammatory disorder of the episclera of eye)
Glomerulonephritis rapidly progressive (a syndrome of the kidney that is characterized by a rapid loss of renal function)
Pulmonary haemorrhage (acute bleeding from the lung)
Vasculitis (inflammation of a blood vessel or blood vessels)
Acute myocardial infarction (acute heart attack)
Cardiac arrest

40-49:

Drug ineffective
Cardiogenic shock (inadequate circulation of blood)
Disease recurrence
Ejection fraction decreased (systolic heart failure)
Electrocardiogram st segment elevation
Hepatic failure (liver failure)
Mental impairment (a condition affecting the body, perhaps through sight or hearing loss, a mobility difficulty or a health condition)
Myopericarditis (disease caused by inflammation of the myocardium (muscle of the heart wall) and/or the pericardium)

50-59:

Pulmonary hypertension (increase in blood pressure in the lung artery)
Bradycardia (abnormally slow heart action)
Cushing's syndrome (obesity, a rounded face, increased fat)
General physical health deterioration (weak health status)
Hyperaldosteronism
Hypotension (abnormally low blood pressure)
Hypoxia (low oxygen in tissues)
Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
Mitral valve incompetence (inefficient heart valve)

60+:

Rhythm idioventricular (a abnormal heart rate)
Sinus node dysfunction (a group of abnormal heart rhythms)

What are the existing conditions these people have? *

Thyrotoxic Crisis (a life threatening condition due to excess secretion of thyroid hormone): 12 people, 60.00%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 4 people, 20.00%
Basedow's Disease (autoimmune disease where the thyroid is overactive, producing an excessive amount of thyroid hormones): 2 people, 10.00%
Ventricular Tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart): 1 person, 5.00%
Urticaria (rash of round, red welts on the skin that itch intensely): 1 person, 5.00%
Tonsillitis (inflammation of tonsil): 1 person, 5.00%
Pneumonia: 1 person, 5.00%
Hypotension (abnormally low blood pressure): 1 person, 5.00%
High Blood Pressure: 1 person, 5.00%
Heart Rate Increased: 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

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