Proscar and Comtan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Proscar (finasteride) and Comtan (entacapone). Common drug interactions include anxiety among males.

The phase IV clinical study analyzes what interactions people have when they take Proscar and Comtan. It is created by eHealthMe based on reports of 34 people who take the same drugs from the FDA, and is updated regularly.

What is Proscar?

Proscar has active ingredients of finasteride. It is often used in prostate examination abnormal. eHealthMe is studying from 13,379 Proscar users. Check the latest studies of Proscar.

What is Comtan?

Comtan has active ingredients of entacapone. It is often used in parkinson's disease. eHealthMe is studying from 3,979 Comtan users. Check the latest studies of Comtan.



On Jul, 10, 2026

34 people who take Proscar and Comtan together, and have interactions are studied.

Proscar and Comtan drug interactions.

What are the common drug interactions of Proscar and Comtan, by gender? *:

female:

n/a

male:

  1. Anxiety
  2. Hallucination (an experience involving the perception of something not present)
  3. Ageusia (loss of taste functions of the tongue)
  4. Agitation (state of anxiety or nervous excitement)
  5. Anaemia (lack of blood)
  6. Aortic valve disease
  7. Arrhythmia (irregular heartbeat)
  8. Cervical spinal stenosis (narrowing of the spinal canal in the neck)
  9. Chest pain
  10. Chills (felling of cold)

What are the common drug interactions of Proscar and Comtan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

  1. Anxiety
  2. Hallucination (an experience involving the perception of something not present)
  3. Arrhythmia (irregular heartbeat)
  4. Cervical spinal stenosis (narrowing of the spinal canal in the neck)
  5. Chest pain
  6. Chills (felling of cold)
  7. Depression
  8. Dizziness
  9. Epistaxis (bleed from the nose)
  10. Essential hypertension (primary hypertension)

What are the existing conditions these people have? *

  1. Hallucinations (sensations that appear real but are created by your mind): 5 people, 14.71%
  2. Urinary Incontinence (inability to control the flow of urine and involuntary urination): 3 people, 8.82%
  3. Orthostatic Hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up): 3 people, 8.82%
  4. Gastrointestinal Disorder (functional problems of gastrointestinal tract): 3 people, 8.82%
  5. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 8.82%
  6. Constipation: 3 people, 8.82%
  7. Respiratory Disorder (respiratory disease): 2 people, 5.88%
  8. On And Off Phenomenon: 2 people, 5.88%
  9. Generalized Anxiety Disorder (excessive, uncontrollable, unexplained and often irrational worry): 2 people, 5.88%
  10. Delusion (a false belief or opinion): 2 people, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Proscar and Comtan?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Proscar and Comtan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Proscar:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Comtan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Proscar and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Comtan and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on finasteride and entacapone (the active ingredients of Proscar and Comtan, respectively), and Proscar and Comtan (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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