Prosom and Oxycontin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Prosom (estazolam) and Oxycontin (oxycodone hydrochloride). Common drug interactions include atrial fibrillation among females and gingival bleeding among males.

The phase IV clinical study analyzes what interactions people have when they take Prosom and Oxycontin. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Prosom?

Prosom has active ingredients of estazolam. It is often used in insomnia. eHealthMe is studying from 340 Prosom users. Check the latest studies of Prosom.

What is Oxycontin?

Oxycontin has active ingredients of oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 212,533 Oxycontin users. Check the latest studies of Oxycontin.

On Jul, 25, 2026

16 people who take Prosom and Oxycontin together, and have interactions are studied.

What are the common drug interactions of Prosom and Oxycontin, by gender? *:

female:

Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Blood cholesterol increased
Cataract (clouding of the lens inside the eye)
Concussion (short loss of normal brain function in response to a head injury)
Fall
Heart rate decreased
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Psychotic disorder
Sick sinus syndrome (a collection of heart rhythm disorders)
Abdominal pain upper

male:

Gingival bleeding (bleeding gums)
Systemic lupus erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue)
Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)
Tooth loss
Type 2 diabetes mellitus
Abdominal discomfort
Drug dependence
Dry mouth
General physical health deterioration (weak health status)
Hypoxic-ischaemic encephalopathy (a condition that occurs when the entire brain is deprived of an adequate oxygen supply, but the deprivation isn't total)

What are the common drug interactions of Prosom and Oxycontin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Diabetes mellitus inadequate control
Hyperglycaemia (high blood sugar)
Type 2 diabetes mellitus
Asthma
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Sinusitis (inflammation of sinus)
Vocal cord thickening

40-49:

Abdominal discomfort
Drug dependence
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Dry mouth
General physical health deterioration (weak health status)
Hypoxic-ischaemic encephalopathy (a condition that occurs when the entire brain is deprived of an adequate oxygen supply, but the deprivation isn't total)
Overdose
Road traffic accident
Somnolence (a state of near-sleep, a strong desire for sleep)
Thrombosis (formation of a blood clot inside a blood vessel)

50-59:

Gingival bleeding (bleeding gums)
Systemic lupus erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Blood cholesterol increased
Cataract (clouding of the lens inside the eye)
Concussion (short loss of normal brain function in response to a head injury)
Fall
Heart rate decreased
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Psychotic disorder

60+:

Chronic kidney disease
Renal failure (kidney dysfunction)
Dysgeusia (disorder of the sense of taste)
Dysuria (painful or difficult urination)
Gastrointestinal pain
Hot flush (sudden feelings of heat)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Migraine (headache)
Nephrogenic anaemia (anaemia due to kidney disease)
Pruritus (severe itching of the skin)

What are the existing conditions these people have? *

Neck Pain: 5 people, 31.25%
Enlarged Prostate: 4 people, 25.00%
Musculoskeletal Stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves): 4 people, 25.00%
Musculoskeletal Pain (pain affects the bones, muscles, ligaments, tendons, and nerves): 4 people, 25.00%
High Blood Pressure: 4 people, 25.00%
Headache (pain in head): 4 people, 25.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 25.00%
Facial Spasm (involuntary muscle contractions face): 4 people, 25.00%
Type 2 Diabetes: 4 people, 25.00%
Oesophagitis (inflammation of oesophagus): 4 people, 25.00%

* Approximation only. Some reports may have incomplete information.

Do you take Prosom and Oxycontin?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously