Protonix and Camptosar drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Protonix (pantoprazole sodium) and Camptosar (irinotecan hydrochloride). Common drug interactions include fatigue among females and death among males.

The phase IV clinical study analyzes what interactions people have when they take Protonix and Camptosar. It is created by eHealthMe based on reports of 53 people who take the same drugs from the FDA, and is updated regularly.

What is Protonix?

Protonix has active ingredients of pantoprazole sodium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 132,658 Protonix users. Check the latest studies of Protonix.

What is Camptosar?

Camptosar has active ingredients of irinotecan hydrochloride. eHealthMe is studying from 7,145 Camptosar users. Check the latest studies of Camptosar.



On Jul, 13, 2026

53 people who take Protonix and Camptosar together, and have interactions are studied.

Protonix and Camptosar drug interactions.

What are the common drug interactions of Protonix and Camptosar, by gender? *:

female:

  1. Fatigue (feeling of tiredness)
  2. Haemoglobin decreased
  3. Hypotension (abnormally low blood pressure)
  4. Anaemia (lack of blood)
  5. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  6. Back pain
  7. Blood glucose increased
  8. Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)
  9. Diarrhoea
  10. Hypocalcaemia (levels of calcium in blood serum are abnormally low)

male:

  1. Death
  2. Nausea (feeling of having an urge to vomit)
  3. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  4. Neutropenia (an abnormally low number of neutrophils)
  5. Pyrexia (fever)
  6. Abdominal hernia
  7. Abscess oral (abscess in the mouth)
  8. Angina unstable (chest pain due to ischemia of the heart muscle- unstable)
  9. Arteriosclerosis (thickening and hardening of arteries)
  10. Atelectasis (partial or complete collapse of the lung)

What are the common drug interactions of Protonix and Camptosar, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Death
  2. Vomiting
  3. Alopecia (absence of hair from areas of the body)
  4. Asthenia (weakness)
  5. Bone marrow failure
  6. Confusional state
  7. Decreased appetite
  8. Dehydration (dryness resulting from the removal of water)
  9. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  10. Diarrhoea

30-39:

n/a

40-49:

  1. Abdominal pain
  2. Anaemia (lack of blood)
  3. Pancreatic carcinoma (pancreatic cancer)
  4. Disease progression
  5. Malignant neoplasm progression (cancer tumour came back)

50-59:

  1. Back pain
  2. Blood glucose increased
  3. Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)
  4. Haemoglobin decreased
  5. Peripheral motor neuropathy (muscles in the body become progressively weaker over months to years)
  6. Sensation of heaviness
  7. Syncope (loss of consciousness with an inability to maintain postural tone)
  8. Urinary incontinence (inability to control the flow of urine and involuntary urination)
  9. Cardiac arrest
  10. Central nervous system lesion (an abnormality in tissue of brain or spinal cord)

60+:

  1. Dyspnoea (difficult or laboured respiration)
  2. Pulmonary embolism (blockage of the main artery of the lung)
  3. Arteriosclerosis (thickening and hardening of arteries)
  4. Atelectasis (partial or complete collapse of the lung)
  5. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  6. Back pain
  7. Bone disorder
  8. Bone neoplasm malignant (cancer of bone)
  9. Bundle branch block right (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the right ventricle)
  10. Cardiomegaly (increased size of heart than normal)

What are the existing conditions these people have? *

  1. Colon Cancer: 11 people, 20.75%
  2. Multiple Myeloma (cancer of the plasma cells): 9 people, 16.98%
  3. Brain Neoplasm Malignant (brain cancer tumour): 7 people, 13.21%
  4. Pancreatic Carcinoma (pancreatic cancer): 4 people, 7.55%
  5. Colon Cancer Metastatic (cancer of colon spreads to other part of body): 4 people, 7.55%
  6. Pain: 3 people, 5.66%
  7. Oesophageal Carcinoma (cancer tumour of oesophagus): 3 people, 5.66%
  8. Nausea (feeling of having an urge to vomit): 3 people, 5.66%

* Approximation only. Some reports may have incomplete information.

Do you take Protonix and Camptosar?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Protonix and Camptosar:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Protonix:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Camptosar:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Protonix and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Camptosar and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on pantoprazole sodium and irinotecan hydrochloride (the active ingredients of Protonix and Camptosar, respectively), and Protonix and Camptosar (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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