Protonix and Cobalamin drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Protonix (pantoprazole sodium) and Cobalamin (vitamin b12). Common drug interactions include upper limb fracture among females and back pain among males.
The phase IV clinical study analyzes what interactions people have when they take Protonix and Cobalamin. It is created by eHealthMe based on reports of 27 people who take the same drugs from the FDA, and is updated regularly.
What is Protonix?
Protonix has active ingredients of pantoprazole sodium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 132,658 Protonix users. Check the latest studies of Protonix.
What is Cobalamin?
Cobalamin has active ingredients of vitamin b12. eHealthMe is studying from 3,429 Cobalamin users. Check the latest studies of Cobalamin.
27 people who take Protonix and Cobalamin together, and have interactions are studied.

What are the common drug interactions of Protonix and Cobalamin, by gender? *:
female:
- Upper limb fracture
- Upper-airway cough syndrome
- Vomiting
- Chronic kidney disease
- Nephropathy (damage to or disease of a kidney)
- Renal failure (kidney dysfunction)
- Anxiety
- Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
- Insomnia (sleeplessness)
- Drug intolerance (drug sensitivity)
male:
- Back pain
- Fatigue (feeling of tiredness)
- Pain
- Cardiomyopathy (weakening of the heart muscle)
- Arteriovenous malformation
- Chest pain
- Choking (mechanical obstruction of the flow of air from the environment into the lungs)
- Dental caries
- Dysphagia (a condition in which swallowing is difficult or painful)
- Intervertebral disc protrusion (spinal disc protrusion)
What are the common drug interactions of Protonix and Cobalamin, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Anxiety
- Palpitations (feelings or sensations that your heart is pounding or racing)
- Precancerous skin lesion
- Surgery
40-49:
- Arteriovenous malformation
- Choking (mechanical obstruction of the flow of air from the environment into the lungs)
- Dental caries
- Drug ineffective
- Dysphagia (a condition in which swallowing is difficult or painful)
- Intervertebral disc protrusion (spinal disc protrusion)
- Microcytic anaemia (a generic term for any type of anaemia characterized by small red blood cells)
- Muscular weakness (muscle weakness)
- Pain
- Palpitations (feelings or sensations that your heart is pounding or racing)
50-59:
- Chest pain
- Epistaxis (bleed from the nose)
- Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
- Neck pain
- Weight increased
- Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
- Aphasia (damage to the parts of the brain that control language)
- Arthralgia (joint pain)
- Arthropathy
- Balance disorder
60+:
- Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
- Fall
- Upper limb fracture
What are the existing conditions these people have? *
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 20 people, 74.07%
- Cataplexy (loss of muscle tone accompanied by full conscious awareness): 7 people, 25.93%
- Pain: 5 people, 18.52%
- Infection: 4 people, 14.81%
- Multiple Allergies (allergy to multiple agents): 3 people, 11.11%
- Kidney Stones: 3 people, 11.11%
- High Blood Cholesterol: 3 people, 11.11%
- Gout (uric acid crystals building up in the body): 3 people, 11.11%
- Fluid Retention (an abnormal accumulation of fluid in the blood): 3 people, 11.11%
* Approximation only. Some reports may have incomplete information.
Do you take Protonix and Cobalamin?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Protonix and Cobalamin:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Protonix:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Cobalamin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Protonix and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Cobalamin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on pantoprazole sodium and vitamin b12 (the active ingredients of Protonix and Cobalamin, respectively), and Protonix and Cobalamin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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