Protonix and Flavin drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Protonix (pantoprazole sodium) and Flavin (riboflavin (vitamin b2)). Common drug interactions include fatigue among females and chronic kidney disease among males.
The phase IV clinical study analyzes what interactions people have when they take Protonix and Flavin. It is created by eHealthMe based on reports of 48 people who take the same drugs from the FDA, and is updated regularly.
What is Protonix?
Protonix has active ingredients of pantoprazole sodium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 132,658 Protonix users. Check the latest studies of Protonix.
What is Flavin?
Flavin has active ingredients of riboflavin (vitamin b2). eHealthMe is studying from 2,870 Flavin users. Check the latest studies of Flavin.
48 people who take Protonix and Flavin together, and have interactions are studied.

What are the common drug interactions of Protonix and Flavin, by gender? *:
female:
- Fatigue (feeling of tiredness)
- Dyspepsia (indigestion)
- Abdominal distension
- Abdominal pain
- Abdominal tenderness
- Anxiety
- Back disorder
- Gallbladder disorder
- Haemorrhage (bleeding)
- Inflammation
male:
- Chronic kidney disease
- Renal injury (kidney injury)
- Pneumonia fungal
- Pulmonary mycosis (lung infection caused by yeast-like fungi)
- Chest pain
- Cough
- Dyspnoea (difficult or laboured respiration)
- Headache (pain in head)
- Parainfluenzae virus infection
- Bacterial infection
What are the common drug interactions of Protonix and Flavin, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
- Bacterial infection
20-29:
- Anxiety
- Drug ineffective
- Nightmare (unpleasant dream)
30-39:
- Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus)
- Dizziness
- Abdominal pain lower
- Back pain
- Dyspepsia (indigestion)
- Flatulence (flatus expelled through the anus)
- Gastroenteritis bacterial (inflammation of stomach and intestine by bacterial infection)
- Lactose intolerance (inability to digest lactose)
- Nasopharyngitis (inflammation of the nasopharynx)
- Productive cough
40-49:
- Cardiomegaly (increased size of heart than normal)
- Chest pain
- Dehydration (dryness resulting from the removal of water)
- Dyspnoea (difficult or laboured respiration)
- Hernia (hernia happens when part of an internal organ or tissue bulges through a weak area of muscle)
- Hypotension (abnormally low blood pressure)
- Palpitations (feelings or sensations that your heart is pounding or racing)
- Peripheral swelling
- Seasonal allergy (allergic condition due to certain season)
- Syncope (loss of consciousness with an inability to maintain postural tone)
50-59:
- Chest pain
- Cough
- Headache (pain in head)
- Oropharyngeal pain
- Dyspnoea (difficult or laboured respiration)
- Parainfluenzae virus infection
- Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
- Anxiety
- Back pain
- Chills (felling of cold)
60+:
- Abdominal distension
- Abdominal pain
- Intestinal perforation (complete penetration of the wall of the intestine)
- White blood cell count increased
- Renal failure (kidney dysfunction)
- Ear infection
- Fall
- Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
- Joint injury
- Pneumonia
What are the existing conditions these people have? *
- Migraine (headache): 7 people, 14.58%
- Immunodeficiency Common Variable: 6 people, 12.50%
- Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 5 people, 10.42%
- High Blood Pressure: 5 people, 10.42%
- Sleep Disorder: 4 people, 8.33%
- Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 8.33%
- Cystic Fibrosis (disease of the secretary glands): 4 people, 8.33%
- Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 3 people, 6.25%
- Psoriasis (immune-mediated disease that affects the skin): 3 people, 6.25%
- Pain: 3 people, 6.25%
* Approximation only. Some reports may have incomplete information.
Do you take Protonix and Flavin?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Protonix and Flavin:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Protonix:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Flavin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Protonix and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Flavin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on pantoprazole sodium and riboflavin (vitamin b2) (the active ingredients of Protonix and Flavin, respectively), and Protonix and Flavin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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