Protonix and Navane drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Protonix (pantoprazole sodium) and Navane (thiothixene). Common drug interactions include oropharyngeal pain among females and type 2 diabetes mellitus among males.

The phase IV clinical study analyzes what interactions people have when they take Protonix and Navane. It is created by eHealthMe based on reports of 51 people who take the same drugs from the FDA, and is updated regularly.

What is Protonix?

Protonix has active ingredients of pantoprazole sodium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 132,658 Protonix users. Check the latest studies of Protonix.

What is Navane?

Navane has active ingredients of thiothixene. It is often used in schizoaffective disorder. eHealthMe is studying from 1,558 Navane users. Check the latest studies of Navane.

On Jul, 09, 2026

51 people who take Protonix and Navane together, and have interactions are studied.

What are the common drug interactions of Protonix and Navane, by gender? *:

female:

Oropharyngeal pain
Pneumonia
Tooth abscess (pus formation in tooth)
Tremor (trembling or shaking movements in one or more parts of your body)
Hyperglycaemia (high blood sugar)
Renal failure (kidney dysfunction)
Anxiety
Arrhythmia (irregular heartbeat)
Asthenia (weakness)
Balance disorder

male:

Type 2 diabetes mellitus
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Psychotic disorder
Schizophrenia, paranoid type (delusions and auditory hallucinations but relatively normal intellectual functioning and expression of affect)
Sinusitis (inflammation of sinus)
Abdominal pain
Chest discomfort
Chest pain
Diabetic coma
Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)

What are the common drug interactions of Protonix and Navane, by age (0-1 to 60+)? *:

0-1:

Balance disorder
Bradycardia (abnormally slow heart action)
Cholecystitis chronic (long lasting infection of gallbladder)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Diabetic complication
Dyspnoea (difficult or laboured respiration)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Hypotension (abnormally low blood pressure)
Nervous system disorder (a general class of medical conditions affecting the nervous system)
Orthopnoea (shortness of breath (dyspnea) when lying down)

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Type 2 diabetes mellitus
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Ill-defined disorder
Hypertension (high blood pressure)
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Schizophrenia, paranoid type (delusions and auditory hallucinations but relatively normal intellectual functioning and expression of affect)
Abdominal pain
Chest discomfort
Chest pain
Depression

40-49:

Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Pancreatitis acute (sudden inflammation of pancreas)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Dyspnoea (difficult or laboured respiration)
Hypokalaemia (low potassium)
Blood cholesterol increased
Obesity (having too much body fat)
Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
Pancreatitis (inflammation of pancreas)
Abdominal pain

50-59:

Depression
Abdominal pain
Anxiety
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cardiac failure congestive
Constipation
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Cough
Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
Headache (pain in head)

60+:

Crying
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Fall
Pain

What are the existing conditions these people have? *

Depression: 24 people, 47.06%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 21 people, 41.18%
Bipolar Disorder (mood disorder): 21 people, 41.18%
Stress And Anxiety: 19 people, 37.25%
Pain: 14 people, 27.45%
Sleep Disorder: 12 people, 23.53%
Agitation (state of anxiety or nervous excitement): 12 people, 23.53%
High Blood Pressure: 11 people, 21.57%
Insomnia (sleeplessness): 8 people, 15.69%
Extrapyramidal Disorder (involuntary muscle spasms in the face and neck): 8 people, 15.69%

* Approximation only. Some reports may have incomplete information.

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